An outstanding, genre-defining work, this book will be read by students, educators, policymakers, scientists, scholars, medical skeptics, and health-care pundits alike. -- John Henning Schumann, MD, host of Public Radio Tulsa's Medical Matters An important book that frames medical reversal in a compelling way. Readers will be drawn to this clearly written account. -- David S. Jones, MD, Harvard University, author of Broken Hearts: The Tangled History of Cardiac Care
Introduction
Part I
Examples, Frequency, and Consequences
1. What Is Medical Reversal?
2. Subjective Outcomes
Why Feeling Better Is Often Misleading
3. Surrogate Outcomes
4. Screening Tests
5. Systems Failure
6. Finding Flawed Therapies on Our Own
7. The Frequency of Medical Reversal
8. The Harms of Medical Reversal
Today's Patients, Tomorrow's Patients, and the Health-Care
Field
Part II
9. A Primer on Evidence-Based Medicine
What Is Evidence in Medicine?
10. What Really Made You Better
When Evidence Gets Complicated
Part III
11. Scientific Progress, Revolution, and Medical Reversal
12. Sources of Flawed Data
13. Why Are We So Attracted to Flawed Therapies?
Part IV
14. Medical Education
A Very Good Place to Start
15. Academic Medicine
16. Reforming the System
The Burden of Proof and Nudging Our Way Past Reversal
17. How Not to Become a Victim of Reversal
18. Beyond Dogma
When Randomized Trials Are Unnecessary
Acknowledgments
Appendix
References
Index
Vinayak K. Prasad, MD, MPH, is a practicing hematologist-oncologist and internal medicine physician at the National Cancer Institute. Adam S. Cifu, MD, is a professor of medicine at the University of Chicago. He is a practicing general internist, medical educator, and the coauthor of Symptom to Diagnosis: An Evidence-Based Guide.
Every doctor should read this book. JAMA Internal Medicine Dr. Prasad and Dr. Cifu offer a five-step plan, including pointers for determining if a given treatment is really able to do what you want it to do, and advice on finding a like-minded doctor who won't object to a certain amount of back-seat driving. Of course, there are no guarantees that their tips will endure forever, but they probably have a longer shelf life than most medical advice. New York Times When I describe Ending Medical Reversal as revolutionary, I don't use the term lightly. Go out and read it-right now. Common Sense Family Dr. ... Should be considered for undergraduate reading lists. Keep a copy in the pharmacy or your briefcase as a great icebreaker or discussion point with other local healthcare professionals. The Pharmaceutical Journal [A]n excellent and realistic discussion of some of the horror stories that occur in medical practice...The examples are quite interesting and certainly educational for all readers. Highly recommended. Choice Ending Medical Reversal goes far in teaching medical students and practicing physicians alike how to learn on our own. The Lancet This has to be on the reading list for medical and nursing students. Nursing Times
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