A concise, approachable overview of the basic concepts of toxicology, this foundational text covers commonly used definitions, historical perspectives, regulatory requirements, good laboratory practices, types of toxicology testing and evaluation, toxic agents and their adverse effects on health, and analytical, forensic, and diagnostic toxicology
Unit I
Chapter 1. Introduction and historical background
Chapter 2. Definitions and scope of toxicology
Chapter 3. Classification of poisons/toxicants
Chapter 4. Factors affecting toxicity
Chapter 5. Natural laws concerning toxicology
Chapter 6. Hazard and risk assessment
Unit II
Chapter 7. Absorption, distribution, and excretion of toxicants
Chapter 8. Biotransformation
Chapter 9. Principles and basic concepts of toxicokinetics
Unit III
Chapter 10. Toxicological testing: Genesis
Chapter 11. Toxicological testing: In vitro models
Chapter 12. Toxicological testing: In vivo systems
Chapter 13. Genotoxicity
Chapter 14. Preclinical toxicological investigations of
pharmaceutical products
Chapter 15. Preclinical safety evaluation of biotechnology-derived
products
Chapter 16. Preclinical regulatory toxicology for biomaterials and
medical devices
Unit IV
Chapter 17. Toxic effects of pesticides (agrochemicals)
Chapter 18. Toxic effects of metals
Chapter 19. Toxic effects of nonmetallics
Chapter 20. Neurotoxic agents
Chapter 21. Toxic effects of cardiac poisons
Chapter 22. Toxic effects of asphyxiants
Chapter 23. Toxic effects of caustics (corrosives)
Chapter 24. Drug toxicity, dependence, and abuse
Chapter 25. Toxic effects of domestic chemicals
Chapter 26. Toxic effects of poisonous plants
Chapter 27. Poisonous foods and food poisoning
Chapter 28. Poisons of animal origin
Chapter 29. Chemical food poisoning
Chapter 30. Health effects of radioactive materials
Unit V
Chapter 31. Basic concepts of forensic toxicology
Chapter 32. Applications in toxicology
Chapter 33. Clinical toxicology
Chapter 34. Treatment of poisoning
Prof. Dr. P.K. (Pawan Kumar) Gupta (BVSc & AH, MVSc, PhD, Hon DSc) obtained his PhD in Toxicology and taught as Visiting Professor at both the University of Tennessee and West Virginia University before returning to India as Professor of Toxicology at the Indian Veterinary Research Institute. He is currently Director of the Toxicology Consulting Group and President of the Academy of Sciences for Animal Welfare. He has served as advisor to the World Health Organization, consultant to the UN Food and Agriculture Organization, and brings more than 50 years of expertise in animal toxicology to the project. He has authored/co-authored more than 10 books, including Elsevier’s Fundamentals of Toxicology (2016), Illustrated Toxicology (2018), and Fundamentals of Nanotoxicology (2022).
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