Table of Contents

Section I; Sequencing approaches to genetic variance detection using different sequencing technologies (BidDye, rhodamine, Pyrosequencing) and respective software analysis tools; Section II; Hybridization based microarray and chip technologies for the detection of genetic variances; Section III; Heteroduplex analysis techniques for genetic variance detection (DHPLC and gel based technologies, chemical and enzymatic cleavage approaches); Section IV; Genetic variance detection using mass spectrometry; Section V; Genetic variance detection using alternate/novel approaches (LCR, Third Wave technology, allele specific PCR, etc.)

About the Author

Karl H Hacker PhD, Editor

Reviews

Genetic Variance Detection - Technologies for Pharmacogenomics is Karl Hecker's second book about technologies for genetic variance detection. It broadly covers a wide range of technologies currently used for genetic variance detection and constitutes an essential contribution to the field. A reference guide for every molecular biology laboratory. His first book Genetic Variance Detection - Nuts & Bolts of DHPLC in Genomics (ISBN 0966402774) provides comprehensive and in depth coverage of denaturing high-performance liquid chromatography and is an invaluable reference for anyone using or planning to use DHPLC for genetic variance detection. -- Norbert Arnold, Professor Dr. rer. nat. University Hospital Schleswig-Holstein, Kiel, Germany