Preface to the Seventh Edition vi
Preface to the First Edition vii
How to use your textbook viii
About the companion website x
1 Haemopoiesis 1
2 Erythropoiesis and general aspects of anaemia 11
3 Hypochromic anaemias 27
4 Iron overload 41
5 Megaloblastic anaemias and other macrocytic anaemias 48
6 Haemolytic anaemias 60
7 Genetic disorders of haemoglobin 72
8 The white cells 1: granulocytes, monocytes and their benign
disorders 87
9 The white cells 2: lymphocytes and their benign disorders 102
10 The spleen 116
11 The aetiology and genetics of haematological malignancies
122
12 Management of haematological malignancy 135
13 Acute myeloid leukaemia 145
14 Chronic myeloid leukaemia 156
15 Myeloproliferative disease 165
16 Myelodysplasia 177
17 Acute lymphoblastic leukaemia 186
18 The chronic lymphoid leukaemias 197
19 Hodgkin lymphoma 205
20 Non-Hodgkin lymphoma 213
21 Multiple myeloma and related disorders 228
22 Aplastic anaemia and bone marrow failure 242
23 Stem cell transplantation 250
24 Platelets, blood coagulation and haemostasis 264
25 Bleeding disorders caused by vascular and platelet abnormalities
278
26 Coagulation disorders 290
27 Thrombosis 1: pathogenesis and diagnosis 302
28 Thombosis 2: treatment 311
29 Haematological changes in systemic disease 321
30 Blood transfusion 333
31 Pregnancy and neonatal haematology 346
Appendix: World Health Organization classification of tumours of
the haematopoietic and lymphoid tissues 352
Index 357
A. Victor Hoffbrand, MA DM FRCP FRCPath FRCP(Edin) DSc FMedSci;
Emeritus Professor of Haematology, University College London;
Honorary Consultant Haematologist, Royal Free Hospital, London,
UK.
Paul A. H. Moss, PhD MRCP FRCPath; Professor of Haematology,
University of Birmingham, Birmingham, UK.
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