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Randomized Clinical Trials of Nonpharmacological Treatments (Chapman & Hall/CRC Biostatistics Series)
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Home » Books » Science » Biology » General

Randomized Clinical Trials of Nonpharmacological Treatments http://www.fishpond.com.au/Books/Randomized-Clinical-Trials-of-Nonpharmacological-Treatments-Isabelle-Boutron-Edited-by-Philippe-Ravaud-Edited-by/9781420088021?cf=3&rid=1152877731&i=16&keywords=paul+glasziou

Chapman & Hall/CRC Biostatistics Series

By Isabelle Boutron (Edited by), Philippe Ravaud (Edited by), David Moher (Edited by)

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Format:Electronic Book Text, 403 pages
Other Information: 22 black & white illustrations, 25 black & white tables
Published In: United States, 05 January 2012
Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval. Consequently, they can be widely proposed in clinical practice but may not have been adequately evaluated. This situation is an important barrier for the evaluation of the beneficial effects of these treatments and the conduct of clinical trials. Randomized Clinical Trials of Nonpharmacologic Treatments focuses on the methods for assessing nonpharmacological treatments, highlighting specific issues and trial design. Features: Chapters written by international experts in the field Highlights specific issues in assessing nonpharmacological treatments in trials including: how to overcome the difficulties of blinding patients, care providers, and outcome assessors the complexity of the intervention, the learning curve, and the clustering effect placebos that can be used issues of assessing harm and assessing the applicability of trials Presents a variety of trial designs for nonpharmacological treatments-including cluster randomized controlled trials, expertise-based trials, pragmatic trials, and nonrandomized trials. Provides several examples of the planning, conduct, analyses, and reporting of trials in different fields, including surgery, technical interventions, medical devices, rehabilitation, psychotherapy, and behavioral interventions. Providing practical examples that underline these issues and solutions, this book is one of the first to exclusively explore this topic, discussing various categories of treatments, from surgical procedures to psychotherapy.

Table of Contents

Assessing Nonpharmacological Treatments: Theoretical Framework Blinding in Nonpharmacological Randomized Controlled Trials Isabelle Boutron and Philippe Ravaud Placebo in Nonpharmacological Randomized Trials Asbjorn Hrobjartsson and Franklin G. Miller Complexity of the Intervention Patricia Yudkin, Rafael Perera, and Paul Glasziou Learning Curves Jonathan A. Cook and Craig R. Ramsay Clustering Effects in RCTs of Nonpharmacological Interventions Jonathan A. Cook Assessment of Harm Panagiotis N. Papanikolaou and John P.A. Ioannidis External Validity and Applicability of Nonpharmacological Trials Isabelle Boutron and Philippe Ravaud Assessing Nonpharmacological Interventions in Cluster Randomized Trials Bruno Giraudeau and Philippe Ravaud Expertise-Based Trials Jonathan A. Cook Pragmatic Trials and Nonpharmacological Evaluation Merrick Zwarenstein Preference Trials Arthur Kangombe, Helen Tilbrook, and David Torgerson Nonrandomized Studies to Evaluate the Effects of a Nonpharmacological Intervention Barnaby C. Reeves Methodological and Reporting Considerations for Systematic Reviews of Nonpharmacological Interventions Alexander Tsertsvadze, Larissa Shamseer, and David Moher Accounting for the Complexity of the Intervention in Nonpharmacological Systematic Reviews Sasha Shepperd and Simon Lewin Reporting Guidelines for Nonpharmacological Trials Isabelle Boutron and Philippe Ravaud Assessing Nonpharmacological Treatments: Practical Examples Assessing Cardiothoracic Surgery: Practical Examples Tom Treasure and Martin Utley Assessing Obstetrics and Gynecology: Practical Examples Vincenzo Berghella and Jorge E. Tolosa Assessing Lower Limb Arthroplasty: Practical Examples David Biau and Remy Nizard Assessing Radiation Therapy: Practical Examples Hidefumi Aoyama Assessing Electroconvulsive Therapy: Practical Examples Keith G. Rasmussen Assessing Acupuncture: Practical Examples Hugh MacPherson Assessing Orthosis: Practical Examples Katherine Sanchez, Claire Jourdan, Francois Rannou, and Serge Poiraudeau Assessing Rehabilitation: Practical Examples Nadine Elizabeth Foster Assessing Psychotherapy: Practical Examples Paula P. Schnurr Assessing Psychosocial Interventions for Mental Health: Practical Examples Graham Thornicroft and Michele Tansella Assessing Behavioral Change Interventions for Mental Health: Practical Examples Charles Abraham Assessing Hypnotherapy: Practical Examples Isabelle Marc Index

Publisher: Chapman & Hall/CRC
ISBN:1420088025
EAN:9781420088021
Age Range: 15+ years
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