List of Contributors, vi
Preface, vii
1 An Overview of Molecular Cancer Pathogenesis, Prognosis,
and Diagnosis, 1
John M. Cullen and Matthew Breen
2 Trimming Tumors for Diagnosis and Prognosis, 27
Paul C. Stromberg and Donald J. Meuten
3 Immunohistochemistry: Fundamentals and Applications
in Oncology, 44
José A. Ramos]Vara and Luke B. Borst
4 Epithelial and Melanocytic Tumors of the Skin,
88
Michael H. Goldschmidt and Kyle H. Goldschmidt
5 Mesenchymal Tumors of the Skin and Soft
Tissues, 142
Mattie J. Hendrick
6 Mast Cell Tumors, 176
Matti Kiupel
7 Tumors of the Hemolymphatic System, 203
Victor E. Valli, Dorothee Bienzle, Donald J. Meuten, and Keith E.
Linder
8 Canine and Feline Histiocytic Diseases, 322
Peter F. Moore
9 Tumors of Joints, 337
Linden E. Craig and Keith G. Thompson
10 Tumors of Bone, 356
Keith G. Thompson and Keren E. Dittmer
11 Tumors of Muscle, 425
Barry J. Cooper and Beth A. Valentine
12 Tumors of the Respiratory Tract, 467
Dennis W. Wilson
13 Tumors of the Alimentary Tract, 499
John S. Munday, Christiane V. Löhr, and Matti Kiupel
14 Tumors of the Liver and Gallbladder, 602
John M. Cullen
15 Tumors of the Urinary System, 632
Donald J. Meuten and Travis L.K. Meuten
16 Tumors of the Genital Systems, 689
Dalen W. Agnew and N. James MacLachlan
17 Tumors of the Mammary Gland, 723
Michael H. Goldschmidt, Laura Peña, and Valentina Zappulli
18 Tumors of the Endocrine Glands, 766
Thomas J. Rosol and Donald J. Meuten
19 Tumors of the Nervous System, 834
Robert J. Higgins, Andrew W. Bollen, Peter J. Dickinson,
and Sílvia Sisó-Llonch
20 Tumors of the Eye, 892
Richard R. Dubielzig
21 Tumors of the Ear, 923
Bradley L. Njaa
Appendix: Diagnostic Schemes and Algorithms, 942
Introduction, 942
Mitotic count, 944
Canine melanomas and melanocytic neoplasms, 946
Histologic grading of canine cutaneous mast cell tumors, 948
Prognosis of canine cutaneous mast cell tumors, 949
Canine subcutaneous mast cell tumors, 951
Cytologic grading of canine cutaneous mast cell tumors, 952
Evaluation of regional lymph node metastasis in canine cutaneous mast cell tumors, 953
Canine oral perioral mast cell tumors, 955
Feline cutaneous mast cell tumors, 956
Canine soft tissue mesenchymal tumor (sarcoma), 957
Canine soft tissue mesenchymal tumor: Future?, 959
Joint tumors in dogs, 960
Lymphoma and lymphoid leukemia prognoses, 961
Enlarged lymph node evaluation in dogs, 965
Bone marrow evaluation, 966
PARR (PCR for antigen receptor rearrangement), 967
Canine and feline nasal tumors, 969
Scoring system and prognosis for canine lung tumors, 970
Histologic grading and prognosis for feline lung tumors, 971
Mammary, 972
Urothelial (transitional) cell carcinoma (UC), 973
Skin masses, 975
Canine breed predispositions for epidermal and melanocytic tumors, 976
Index, 979
Donald J. Meuten, DVM, PhD, Diplomate ACVP, is Professor Emeritus at the College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
"The fifth edition of Tumors in Domestic Animals has some
substantial changes from the previous edition, the most immediately
striking of which is the inclusion of color, which greatly adds to
the illustrative power of the images. This edition contains several
new chapters and updates to other chapters. Particularly noteworthy
are the new chapters on trimming tissue specimens for submission
and immunohistochemistry and updates to chapter 1, the section on
lymphoma, and the diagnostic and prognostic algorithms in the
appendices. Overall, the information contained in this book
reflects the substantial progress made in veterinary oncology
during the 15 years since the previous edition was released".....
"Overall, this book is reasonably priced and should be in the
library of anyone with an interest in veterinary pathology or
clinical oncology." (Reviewed by Claire Cannon, BVSc, DACVIM,
University of Minnesota 15th June 2017 AVMA)
“Tumors in domestic animals commences with a brief introduction to
cancer biology, followed by a discussion of the processes required
for tissue specimens to be examined by pathologists, including
trimming tumours and margin evaluation. This information is
invaluable for clinicians to ensure they provide the most useful
samples, allowing pathologists to make the most accurate
diagnosis....This text will be a welcome addition to every small
animal veterinarian’s library, but particularly so for those with a
keen interest in oncology and pathology.” -Australian Veterinary
Journal Vol.96, No. 12, December 2018
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