Table of Contents

Preface Chapter 1. Historical introduction and overview Chapter 2. Collecting and storing sequences in the laboratory Chapter 3. Alignment of pairs of sequences Chapter 4. Introduction to probability and statistical analysis of sequence alignments Chapter 5. Multiple sequence alignment Chapter 6. Sequence database searching for similar sequences Chapter 7. Phylogenetic prediction Chapter 8. Prediction of RNA secondary structure Chapter 9. Gene prediction and regulation Chapter 10. Protein classification and structure prediction Chapter 11. Genome analysis Chapter 12. Bioinformatics programming using Perl and Perl modules Chapter 13. Analysis of microarrays

Reviews

"Bioinformatics is an excellent text for the biologist who wants to learn more about the field, and is well worth exploring by the instructor looking to tackle his or her first bioinformatics course." - Nature Genetics" "...an excellent textbook for bioinformatics introductory courses for both life sciences and computer science students, and a good reference for current problems in the field and the tools and methods employed in their solution." --Briefings in Bioinformatics