Table of Contents

Introduction; Part I. An Overview of Functional Magnetic Resonance Imaging: I A. Introduction to Functional Neuroimaging: 1. Energy metabolism in the brain; 2. Cerebral blood flow; 3. Brain activation; I B. Introduction to Functional Magnetic Resonance Imaging: 4. Nuclear magnetic resonance; 5. Magnetic resonance imaging; 6. Imaging functional activity; Part II. Principles of Magnetic Resonance Imaging: II A. The Nature of the Magnetic Resonance Signal: 7. Basic physics of magnetism and NMR; 8. Relaxation and contrast in MRI; 9. Diffusion and the MR signal; II B. Magnetic Resonance Imaging: 10. Mapping the MR signal; 11. MRI techniques; 12. Noise and artifacts in MR images; Part III. Principles of Functional Magnetic Resonance Imaging: III A. Perfusion Imaging: 13. Principles of tracer kinetics; 14. Contrast agent techniques; 15. Arterial spin labeling techniques; III B. Blood Oxygenation Level Dependent (BOLD) Imaging: 16. The nature of the BOLD effect; 17. Mapping brain activation with BOLD-fMRI; 18. Statistical analysis of BOLD data; 19. Efficient design of BOLD experiments; Appendix: the physics of NMR; Index.

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This is an invaluable introduction to Functional Magnetic Resonance Imaging for an interdisciplinary range of medical professionals.

Reviews

'… can be highly recommended to clinical researchers and all specialists in the field of functional MRI.' European Radiology

'Buxton has an art of taking complex concepts and describing them in simple words, without oversimplifying them, using images and metaphors in a very sound way … For all of us using fMRI techniques in our research, this book is a must for our libraries. Who would have guessed that a physics textbook about fMRI could be a pleasure to read.' TRENDS in Neurosciences

' … an excellent book about MRI and its clinical applications. … covers the important points in a superb manner.' British Journal of Neurosurgery

'The chapter on statistical analysis of fMRI data guides one through this complicated method in such a way that the principles become clear. The book itself would prove very helpful to both those who are beginners in the field but also, to experienced researchers of fMRI, as a good, detailed view of the principles and techniques involved in fMRI.' Addiction Biology