Table of Contents

I. Overview of the Frontal Lobes
1. The Human Frontal Lobes: An Introduction, Bruce L. Miller
2. Conceptual and Clinical Aspects, Jeffrey L. Cummings and Bruce L. Miller
II. Anatomy
3. Frontal-Subcortical Circuits, Tiffany W. Chow and Jeffrey L. Cummings
4. The Dorsolateral and Cingulate Cortex, Daniel I. Kaufer
5. The Orbitofrontal Cortex and the Insula, Jennifer Ogar and Maria Luisa Gorno-Tempini
6. Structural and Functional Asymmetries of the Human Frontal Lobes, Daniel H. Geschwind and Marco Iacoboni
7. Gross Morphology and Architectonics, Danielle Andrea Carlin
8. Evolution of the Frontal Lobes, Harry J. Jerison
III. Neurochemistry
9. Serotonin and the Frontal Lobes, Philippe H. Robert, Michel Benoit, and Hervé Caci
10. Oiling the Gears of the Mind: Roles for Acetylcholine in the Modulation of Attention, Serena Amici and Adam L. Boxer
11. The Mesocortical Dopaminergic System, Antonello Bonci and Susan Jones
IV. Functional and Structural Imaging Approaches
12. Structural Imaging of the Frontal Lobes, Howard Rosen and David Dean
13. Unifying Prefrontal Cortex Function: Executive Control, Neural Networks, and Top-Down Modulation, Adam Gazzaley and Mark D'Esposito
14. Insight into Frontal Lobe Function from Functional Neuroimaging Studies of Episodic Memory, W. Dale Stevens and Cheryl L. Grady
15. The Frontal Lobes and Autobiographical Memory, Margaret C. McKinnon, Eva Svoboda, and Brian Levine
16. Planning and the Brain, Jordan Grafman
17. Principles of Motor Control by the Frontal Lobes as Revealed by the Study of Voluntary Eye Movements, Adam L. Boxer
V. Neuropsychological Functions
18. Bedside Frontal Lobe Testing, Joel H. Kramer and Lovingly Quitania
19. New Approaches to Prefrontal Lobe Testing, Donald T. Stuss
20. Language and Frontal Cortex, Argye E. Hillis
21. Self-Representation and the Frontal Lobes, William W. Seeley and Virginia E. Sturm
22. Frontal Dysfunction and Capacity to Consent to Treatment or Research: Conceptual Considerations and Empirical Evidence, LauraB. Dunn, Barton W. Palmer, and Jason H. T. Karlawish
23. Social Cognition in Frontal Injury, Katherine P. Rankin
VI. Neurological Diseases
A. Frontotemporal Dementia and Related Disorders
24. Clinical Aspects of Frontotemporal Dementia, Pei-Ning Wang and Bruce L. Miller
25. Genetics and Neuropathology of Frontotemporal Dementia, Nigel J. Cairns, Virginia M.-Y. Lee, and John Q. Trojanowski
26. Imaging in Frontotemporal Dementia, Murray Grossman
27. Progressive Supranuclear Palsy, Corticobasal Degeneration, and the Frontal Cortex, Irene van Balken and Irene Litvan
28. Frontal Variant of Alzheimer's Disease, Julene K. Johnson, Arne Brun, and Elizabeth Head
B. Other Neurological Disorders
29. Vascular Disease of the Frontal Lobes, Ae Young Lee and Helena Chui
30. Parkinson's Disease with and without Dementia and Lewy Body Dementia, Bruno Dubois, Bernard Pillon, and Ian G. McKeith
31. Neurosurgical Intervention for Psychiatric Illness: Past, Present, and Future, Anthony P. Weiss, Scott L. Rauch, and Bruce H. Price
32. Infectious, Inflammatory, and Demyelinating Disorders, Douglas W. Scharre
33. Traumatic Brain Injury, Judith Aharon-Peretz and Rachel Tomer
34. Adult-Onset Genetic Disorders Involving the Frontal Lobes, Michael D. Geschwind, Grace Yoon, and Jill Goldman
35. Frontal Lobe Development in Childhood, Carole Samango-Sprouse
VII. Psychiatric Diseases
36. Frontal Lobe Functioning in Schizophrenia: Evidence from Neuropsychology, Cognitive Neuroscience, and Psychophysiology, Susan A. Legendre Ropacki and William Perry
37. Bipolar Disorder and the Frontal Lobes, Mary G. DeMay, Danijela Pavlic, and Bruce L. Miller
38. Obsessive-Compulsive Disorder and the Frontal Lobes, Denys Fontaine, Vianney Mattei, and Philippe H. Robert
39. Depression and the Frontal Lobes, Ira M. Lesser and Julia A. Chung

About the Author

Edited by Bruce L. Miller, MD, Memory and Aging Center, Department of Neurology, University of California, San Francisco, USA; and Jeffrey L. Cummings, MD, Department of Neurology and Alzheimer's Disease Center, University of California, Los Angeles, USA

Reviews

"This excellent book has tackled an enormous literature in a fascinating and comprehensive manner. The editors should be commended for their detailed and accessible treatment of a complex and ever growing area. I would wholeheartedly recommend this book to all psychologists with an interest in the human frontal lobes." - Dr Niall Pender, Principal Clinical Neuropsychologist and Head of the Department of Psychology at Beaumont Hospital, Dublin, Ireland 'A well-written and comprehensive text from two eminent clinical neuroscientists. In keeping with a tradition of excellence, this second edition expands on the editors' highly successful first edition. A historical and conceptual overview has been added, as well as a new section on imaging that includes contributions from foremost experts. Advances in the understanding of frontotemporal dementia are also reflected in chapters emphasizing the importance of this previously understudied disease. This text is a 'must read' for anyone seriously interested in understanding the biology of behavior and the diseases that cause it to go awry.' - Charles DeCarli, MD, Department of Neurology and Center for Neuroscience, University of California, USA 'Few areas of the brain have attracted more research than the frontal lobes. Once considered esoteric, frontal lobe disease is now a common diagnosis in patients with neurodegenerative dementias. This updated second edition, edited by two prominent leaders in behavioral and cognitive neurology, contains a thoughtfully integrated exploration of frontal lobe neuroanatomy, neurochemistry, imaging, and neuropsychology. The contributors include some of the most productive clinicians and scientists in the field. Drs. Miller and Cummings have edited a volume that deserves to become the standard reference work on the human frontal lobes.' - Marsel Mesulam, MD, Cognitive Neurology and Alzheimer's Disease Center, Feinberg School of Medicine, Northwestern University, USA 'This second edition provides the perfect framework for further integrating neurology, psychiatry, and neuropsychology in the understanding and treatment of major mental disorders. A great breadth of scientific knowledge, clinical acumen, and provocative analysis is brought to bear on enigmatic frontal lobe syndromes. Detailed and comprehensive, this is a vital reference for practitioners, investigators, and students who wish to be at the cutting edge of clinical neuroscience and multidisciplinary research.' - Paul Eslinger, PhD, Penn State Hershey Medical Center, USA