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Antibody Therapeutics


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Table of Contents

Antibodies as Therapeutics
Unconjugated Antibodies as Therapeutics, M. Clark
Immunotoxins for Treating Cancer and Autoimmune Disease, R.J. Kreitman and I. Pastan
Antibodies as Carriers for Drug and Radioisotopes, G. Yarranton
Tumor Targeting by Antibody-Drug Conjugates, I. Benhar and I. Pastan
Application of Antibody Therapeutics
Therapeutic Antibodies in Infectious Disease, W.J. Harris
Antibody Therapeutics: Application to Autoimmunity, L. Chatenoud
Monoclonal Antibodies in Transplantation, M.-L. Alegre
Development of Antibody Therapeutics
Regulatory Issues for the Development of Antibody Therapeutics, K.J. Lambert
Manufacture of Antibodies by Large Scale Mammalian Cell Culture, D.K. Robinson, V. Yabannavar, and Y. Deo
Production of Antibody Domains in Prokaryotes, M. Better and P. Gavit
Emerging Production Systems for Antibody Therapeutics, A.J.R. Porter, K.J. Bentley, P.M. Cupit, and T.P. Wallace
Recombinant Antibodies in the Clinic
Development of Zenapax (TM): A Humanized Anti-Tac Antibody, J. Hakimi, D. Mould, T.A. Waldmann, C. Queen, C. Anasetti, and S. Light
Progress with a Reshaped Monoclonal Antibody, RSHZ19, for the Prophylaxis and Treatment of Respiratory Syncytial Virus Infection, S.B. Dillon and T.G. Porter
CDP571, An Engineered Antibody to Human Tumor Necrosis Factor, S. Stevens, O. Vetterlein, and M. Sopwith
The Therapeutic Potential of a Primatized (R), Nondepleting Anti-CD4 (IDEC-CE9.1) Monoclonal Antibody in Rheumatoid Arthritis, A.M. Solinger, A. Truneh, J.A. Lipani, and R.A. Newman

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