Table of Contents

What is 'pharmaceutics'?

Design of dosage forms

PART ONE: SCIENTIFIC PRINCIPLES OF DOSAGE FORM DESIGN

*Dissolution and solubility
*Properties of solutions
*Rheology
*Surface and interfacial phenomena
*Disperse systems
*Kinetics of product stability

PART TWO: PARTICLE SCIENCE AND POWDER TECHNOLOGY

*Solid-state properties
*Particle size analysis
*Particle size reduction
*Particle size separation
*Mixing
*Powder flow.

PART THREE: PHARMACEUTICAL MICROBIOLOGY AND STERILIZATION

*Fundamentals of microbiology
*Pharmaceutical applications of microbiological techniques
*Action of physical and chemical agents on microorganisms
*Principles of sterilization
*Sterilization in practice

PART FOUR: BIOPHARMACEUTICAL PRINCIPLES OF DRUG DELIVERY

*Introduction to biopharmaceutics
*The gastrointestinal tract - physiology and drug absorption
*Bioavailability - physicochemical and dosage form factors
*Assessment of biopharmaceutical properties
*Dosage regimens

PART FIVE: DOSAGE FORM DESIGN AND MANUFACTURE

*Pharmaceutical preformulation
*Solutions
*Clarification
*Suspensions and emulsions
*Powders and granules
*Granulation
*Drying
*Tablets and compaction
*Modified-release peroral dosage forms
*Coating of tablets and multiparticulates
*Hard gelatin capsules
*Soft gelatin capsules
*Pulmonary drug delivery
*Nasal drug delivery
*Transdermal drug delivery
*Wound dressings
*Rectal and vaginal drug delivery
*Delivery of pharmaceutical proteins
*Packs and packaging
*Microbiological contamination, spoilage and preservation of medicines
*Product stability and stability testing
*Pharmaceutical plant design
*Heat transfer and the properties and use of steam