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Basic and Applied Bone Biology

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Introductory resource for graduate students, professors, and new researchers of skeletal biology

Table of Contents

Basic Bone Biology and Physiology Chapter 1: Bone morphology and organization Chapter 2: Bone cells Chapter 3: Local regulation of bone cell function Chapter 4: Bone modeling and remodeling Assessment of Bone Structure and Function Chapter 5: Skeletal imaging Chapter 6: Skeletal hard tissue biomechanics Chapter 7: Techniques in histomorphometry Chapter 8: Skeletal genetics Skeletal adaptation Chapter 9: Mechanical adaptation Chapter 10: Fracture healing Chapter 11: Craniofacial biology, orthodontics, and implants Hormonal and Metabolic Effects on Bone Chapter 12: Skeletal growth and development Chapter 13: Calcium and phosphate: Hormonal regulation and metabolism Chapter 14: Nutrition Chapter 15: Hormonal effects on bone cells Skeletal disease and treatment Chapter 16: Metabolic bone diseases Chapter 17: Pharmaceutical treatments of osteoporosis

About the Author

David B. Burr is a University Distinguished Professor of Anatomy and Cell Biology at Indiana University School of Medicine, and Professor of Biomedical Engineering at IUPUI. He joined the Indiana University School of Medicine faculty in 1990 as Chair of the Department of Anatomy (1990-2010), following faculty positions at the University of Kansas and West Virginia University Medical Schools. He served as President of the American Association of Anatomists (2007-2009) and the Orthopaedic Research Society, and is the Director of the IBMS Sun Valley Workshop on Musculoskeletal Biology. He is a fellow of the American Association of Anatomists, and serves as Editor-in-Chief for Current Osteoporosis Reports, Associate Editor for Bone and the J of Musculoskeletal and Neuronal Interactions. He is the author of more than 230 research articles in the peer- reviewed literature, 48 book chapters and reviews, and four books on the structure, function and mechanics of bone. Matthew R. Allen is an Associate Professor of Anatomy and Cell Biology at Indiana University School of Medicine. His research career, and interest in bone biology, began at Alma College during a summer research fellowship and continued during his years as a PhD student at Texas A&M (in Kinesiology) and post-doctoral fellow at IU School of Medicine. His research focuses on understanding how interventions can be maximized to strengthen the skeleton and his teaching duties include Medical Histology (to first year medical students) and Basic Bone Biology (to graduate students). He serves on the Editorial Board for the Journal of Bone and Mineral Research, BONE, and BoneKEY, and as an Associate Editor for Clinical Reviews in Bone and Mineral Metabolism. He has authored more than 70 research articles and 18 book chapters and reviews.


"Basic and Applied Bone Biology provides a comprehensive background of bone science and related research techniques. Topics covered include bone physiology, biomechanics, histomorphometry, skeletal imaging, genetics, and fracture healing; in addition, clinical areas such as metabolic bone diseases and the pharmacological treatment of osteoporosis are discussed. The book is concise, clearly written and beautifully illustrated and will be an invaluable source of information for basic and clinical researchers!" Juliet Compston, Professor of Bone Medicine, University of Cambridge, School of Clinical Medicine and Addenbrooke's NHS Trust, Deptartment of Medicine, Cambridge, United Kingdom "I have enjoyed instructing graduate students and orthopedic residents in bone physiology but a reoccurring frustration has been the lack of a comprehensive textbook. I was delighted to learn that Drs. Burr and Allen were editing a textbook, Basic and Applied Bone Biology, and found the quality of the presentation to actually exceed my high expectations. The text is very readable and the illustrations informative and exceptionally clear. Based on the diversity of topics I reviewed, this book will be useful for all scientists engaged in bone research as well as students new to the discipline. I look forward to including it in my personal library as well as using it as a textbook!" Russell T. Turner, PhD, Professor and Director, Skeletal Biology Laboratory, College Of Public Health and Human Sciences, Oregon State University, Oregon, USA

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