COVID-19 Response at

Read what we're doing...

The Bioarchaeology of Metabolic Bone Disease


Product Description
Product Details

Promotional Information

This is the first book that concentrates exclusively on metabolic bone diseases in archaeological human bone.

Table of Contents

Acknowledgments Foreword Chapter 1. Introduction Metabolic Bone Disease: A Definition Format of the Book Chapter 2. The Study of Metabolic Bone Disease in Bioarchaeology Approaches to the Study of Metabolic Bone Disease Challenges in the Investigation of Metabolic Bone Disease Museum Collections Archaeological Human Bone Paleopathological Diagnoses Demographic Issues Modern Medical Data Genetics and Anthropology Cultural and Social Anthropology Nutritional and Medical Anthropology Primatology Conclusions Chapter 3. Background to Bone Biology and Mineral Metabolism Bone Tissue: Cortical and Trabecular Bone Different Types of Bone Structure: Woven Bone and Lamellar Bone Bone Cells Modeling and Remodeling: Growth and Adulthood Mechanisms of Growth Modeling Remodeling Bone Mineralization: The Extracellular Matrix (osteoid) Tooth Formation and Mineralization Reasons for Remodeling Box Feature 3.1. Bone Biology in Context of the Life Course Bone Biology in Fracture Healing Mineral Metabolism during Life Extracellular Mineral Metabolism Conclusions Chapter 4. Vitamin C Deficiency Scurvy Causes of Vitamin C Deficiency Sources of Vitamin C Box Feature 4.1. Scurvy and Weaning The Role of Vitamin C Vitamin C Requirements Consequences of Scurvy Consequences for Adults Consequences for Children Scurvy in the Modern Perspective Anthropological Perspectives Reference to Probable Scurvy in Early Texts Box Feature 4.2. Subsistence Change and the Development of Scurvy: The Origins of Agriculture A More Recent View of Scurvy in the Past Paleopathological Cases of Scurvy Diagnosis of Scurvy in Archaeological Bone Macroscopic Features of Infantile Scurvy Macroscopic Features of Adult Scurvy Radiological Features of Infantile Scurvy Radiological Features of Adult Scurvy Histological Features of Infantile Scurvy Histological Features of Adult Scurvy Differential Diagnosis Box Feature 4.3. Scurvy in Non-Human Primates: A Result of Human Actions Conclusions Appendix: Summary of Published Archaeological Evidence for Vitamin C Deficiency Chapter 5. Vitamin D Deficiency The Skeletal Requirement of Vitamin D Terminology Causes of Vitamin D Deficiency Sunlight Cultural Practices and Sunlight Exposure Skin Pigmentation and Genetic Adaptations Food Sources Pregnancy and Lactation Increased Age Age-Related Osteoporosis Additional Causes of Vitamin D Deficiency with Effects on Mineral Metabolism Rickets Consequences of Rickets Historical Recognition of Rickets Rickets in the Modern Perspective Anthropological Perspectives: Rickets Box Feature 5.1. Beyond Fighting: The Physiological Impact of Warfare Paleopathological Cases of Rickets Diagnosis of Rickets in Archaeological Bone Macroscopic Features of Rickets Radiological Features of Rickets Histological Features of Rickets Residual Rickets in the Anthropological Perspective: Adult Evidence of Childhood Vitamin D Deficiency Diagnosis of Residual Rickets in Archaeological Bone Macroscopic Features of Residual Rickets Radiological Features of Residual Rickets Histological Features of Rickets Co-Morbidities Differential Diagnosis Vitamin D Deficiency Osteomalacia Pseudofractures Adult Vitamin D Deficiency in the Modern Perspective Box Feature 5.2. Physical and Non-Violent Manifestations of Abuse Anthropological Perspectives: Osteomalacia Paleopathological Cases of Osteomalacia Diagnosis of Osteomalacia in Archaeological Bone Macroscopic Features of Osteomalacia Radiological Features of Osteomalacia Histological Features of Osteomalacia Conclusions Appendix: Summary of Published Archaeological Evidence for Vitamin D Deficiency Chapter 6. Age-Related Bone Loss and Osteoporosis Definitions of Osteoporosis Causes of Age-Related Osteoporosis Menopause Increased Age Peak Bone Mass Mechanical Loading Extremes of Exercise Continuing Sub-Periosteal Apposition Genetics and Population Groups Nutrition and Lifestyle Skeletal Features of Age-Related Osteoporosis Consequences of Age-Related Osteoporosis: Fractures Distal Radius Fractures (Colles ' Fractures) Vertebral Fractures Femoral Fractures Osteoporosis in the Modern Perspective Anthropological Perspectives Box Feature 6.1. Historical and Anthropological Perspectives of Aging Age-Related Osteoporosis in Men Box Feature 6.2. Animal Studies in Osteoporosis I: Age-Related Bone Loss Box Feature 6.3. Problems in the Determination of Age-Related Bone Changes in Biological Anthropology Paleopathological Cases of Age-Related Osteoporosis Co-Morbidities Diagnosis of Age-Related Bone Loss and Osteoporosis in Archaeological Bone Macroscopic Features of Osteoporosis Radiological Features of Osteoporosis Histological Changes of Osteoporosis Conclusions Chapter 7. Secondary Osteopenia and Osteoporosis Causes of Secondary Osteopenia and Osteoporosis Osteopenia and Mobility Effects of Immobilization Box Feature 7.1. Animal Studies in Osteoporosis II: Immobilization-Related Osteopenia Trauma and Causes of Immobility Non-Long Bone Trauma and Additional Causes of Disuse Osteoporosis Bone Loss in Infectious Diseases Immobility in Viral Conditions Congenital and Developmental Conditions Osteopenia in Spinal Cord or Neuromuscular System Afflictions Box Feature 7.2. Implications of Immobility and Inferences of Disability Osteopenia in Pathological Conditions Joint Disease Hematopoietic Conditions Neoplastic and Malignant Conditions The Influence of Diet on Osteoporosis Risk Dietary Acid Load and Proposed Mechanisms of Bone Loss Calcium Protein Fatty Acids Fruit and Vegetables Anthropological Perspectives Calcium in the Evolutionary Perspective The Effect of Meat Eating on Calcium Adequacy Box Feature 7.3. The Health of Adaptive and Transitional Diets: Integrated Approaches? Calcium Availability with the Onset of Domestication Diagnosis of Secondary Osteopenia in Archaeological Bone Conclusions Chapter 8. Paget's Disease of Bone POSSIBLE CAUSES OF PAGET'S DISEASE Box Feature 8.1. Animal Paleopathology Consequences of Paget's Disease Pelvic Changes Cranial Changes Long Bone Changes Other Bones that can be Affected Co-Morbidities Paget's Disease in the Modern Perspective Age and Sex Geographic Variation Anthropological Perspectives Paleopathological Cases of Paget's Disease Diagnosis of Paget's Disease in Archaeological Bone Macroscopic Features of Paget's Disease Radiological Features of Paget's Disease Histological Features of Paget's Disease Differential Diagnosis Box Feature 8.2. The Contribution of Paleopathology to Modern Medicine Conclusions Chapter 9. Miscellaneous Conditions Fluorosis Consequences of Fluorosis Dental Fluorosis Skeletal Fluorosis Co-Morbidities Fluorosis in the Modern Perspective Anthropological Perspectives: Fluorosis Paleopathological Cases of Fluorosis Other Conditions Linked to Intoxication Hyperparathyroidism Causes of Hyperparathyroidism Primary Hyperparathyroidism Secondary Hyperparathyroidism Consequences of Hyperparathyroidism Anthropological Perspectives: Hyperparathyroidism Paleopathological Cases of Hyperparathyroidism Diagnosis of Hyperparathyroidism in Archaeological Bone Pellagra Box Feature 9.1. Anthropological Investigations of Displaced Peoples Starvation Box Feature 9.2. Malnutrition, Starvation and Osteoporosis Rare Metabolic Bone Diseases Hyperostosis Hypophosphatasia Osteogenesis Imperfecta Osteopetrosis Conclusions Chapter 10. Overview and Directions for Future Research Bone Biology Vitamin C Deficiency, Scurvy Vitamin D Deficiency, Rickets and Osteomalacia Age-Related Osteoporosis Secondary Osteopenia and Osteoporosis Paget'S Disease of Bone Miscellaneous Metabolic Bone Diseases Conclusions Bibliography Index

About the Author

Megan B. Brickley is currently Professor and Tier 1 Canada Research Chair in the Bioarchaeology of Human Disease at the Department of Anthropology, McMaster University, Canada. Her primary research interests are use of paleopathology in bioarchaeology, and interdisciplinary research on past human health and disease. She has served as past-Chair of the British Association of Biological Anthropology and Osteoarchaeology and an Associate Editor of American Journal of Physical Anthropology. Currently she is an Associate Editor of the International Journal of Paleopathology and the President Elect of the Paleopathology Association. Her publications include two co-authored and six edited books and eighty journal papers and book chapters. Dr Rachel Ives is the Curator of Anthropology in the department of Earth Sciences at the Natural History Museum, London. She is responsible for the curation of the palaeoanthropology, fossil primate, human remains, and artefact collections and promotes scientific research, exhibitions, and outreach access to the collections. Rachel's research interests are in bone cell biology together with skeletal palaeopathology, particularly the metabolic bone diseases and disease co-occurrence. Rachel has carried out large-scale surveys of metabolic bone diseases in urban contexts and was a post-doctoral researcher on a Calleva Foundation funded Child Health project at the NHM, investigating how the skeleton changes during childhood growth and in response to pathology. Rachel previously worked in the commercial sector carrying out archaeological cemetery excavations and osteological analyses, and she continues work in osteoarchaeological consultancy for heritage development projects.


"[Bioarchaeology of Metabolic Bone Disease] takes us along a fascinating exploratory journey of the main (and not so common) metabolic bone diseases identifiable in skeletal remains. Useful supporting tables, and clear photographic images and line drawings, supplement the text, with a concluding chapter providing a view of future research...." --Professor Charlotte A. Roberts, Department of Archaeology, Durham University "The authors' cogent discussion of how elements within a given lifestyle, including diet/nutrition, cultural practices, socio-economic status, and the surrounding environment, can significantly impact the health of individuals and of societies is illustrated with abundant well-chosen anthropological examples. This volume will be of great value to all scholars devoted to accurate, informative reconstructions of past human life." --Mary Lucas Powell, Ph.D., Past Editor, Paleopathology Newsletter, The Paleopathology Association

Ask a Question About this Product More...
Write your question below:
Look for similar items by category
People also searched for
How Fishpond Works
Fishpond works with suppliers all over the world to bring you a huge selection of products, really great prices, and delivery included on over 25 million products that we sell. We do our best every day to make Fishpond an awesome place for customers to shop and get what they want — all at the best prices online.
Webmasters, Bloggers & Website Owners
You can earn a 5% commission by selling The Bioarchaeology of Metabolic Bone Disease on your website. It's easy to get started - we will give you example code. After you're set-up, your website can earn you money while you work, play or even sleep! You should start right now!
Authors / Publishers
Are you the Author or Publisher of a book? Or the manufacturer of one of the millions of products that we sell. You can improve sales and grow your revenue by submitting additional information on this title. The better the information we have about a product, the more we will sell!
Item ships from and is sold by Fishpond Retail Limited.
Back to top