I. THE REALM OF BIOCHEMISTRY. 1. The Scope of Biochemistry.
2. The Matrix of Life: Weak Interactions in an Aqueous Environment.
3. The Energetics of Life.
II. MOLECULAR ARCHITECTURE OF LIVING MATTER. 4. Nucleic Acids.
5. Introduction to Proteins: The Primary Level of Protein Structure.
6. The Three- Dimensional Structure of Proteins.
7. Protein Function and Evolution.
8. Proteins in Motion: Contractile Systems and Molecular Motors.
10. Lipids, Membranes, and Cellular Transport.
III. DYNAMICS OF LIFE: CATALYSIS AND CONTROL OF BIOCHEMICAL REACTIONS. 11. Enzymes: Biological Catalysts.
12. Introduction to Metabolism.
IV. DYNAMICS OF LIFE: ENERGY, BIOSYNTHESIS, AND UTILIZATION OF PRECURSORS. 13. Carbohydrate Metabolism I: Anaerobic Processes in Generating Metabolic Energy.
14. Oxidative Processes: Citric Acid Cycle and Pentose Phosphate Pathway.
15. Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism.
16. Carbohydrate Metabolism II: Biosynthesis.
18. Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins.
19. Lipid Metabolism II: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids.
20. Metabolism of Nitrogenous Compounds: Principles of Biosynthesis, Utilization, and Turnover.
21. Metabolism of Nitrogenous Compounds: Amino Acids, Porphyrins, and Neurotransmitters.
22. Nucleotide Metabolism.
23. Metabolic Coordination, Metabolic Control, and Signal Transduction
V. INFORMATION. 24. Information Copying: Replication.
25. Information Restructuring: Restriction, Repair, Recombination, Rearrangement, and Amplification.
26. Information Readout: Transcription.
27. Information Decoding: Translation.
28. Eukaryotic Genes and Their Expression.
Answers to Problems.
Christopher K. Mathews is Distinguished Professor and Chairman of
the Department of Biochemistry and Biophysics at Oregon State
University. Dr. Mathews was an Eleanor Roosevelt International
Cancer Fellow at the Karolinska Institute in Stockholm in 1984-85
and Tage Erlander Guest Professor at Stockholm University in
1994-95. He has published several books and more than 125
scientific papers dealing with molecular virology, metabolic
regulation, nucleotide enzymology, and biochemical genetics.K.E.
van Holde is Distinguished Professor Emeritus of Biophysics and
Biochemistry at Oregon State University. Dr. van Holde's major
research interest is the structure of chromatin; his work resulted
in theaward of an American Cancer Society Research Professorship in
1977 and hiselection to the National Academy of Sciences in 1989.
He has received Guggenheim, NSF, and EMBO Fellowships and is the
author of two books and more than 175 scientific papers.Kevin Ahern
is a Senior Instructor in the Department of Biochemistry and
Biophysics at Oregon State University, where he pioneered the
development of Web-based courses for teaching biochemistry. He is a
contributing editor to Science magazine and a columnist for Genetic
Engineering News. He has edited two books, Biotechnology
Software Reports - Computer Applications for Molecular
Biologists and The Biotechnology Software Directory, A
Buyer's Guide, and is the founder of DaVinci Press Ink, a
scientific software consulting firm. Dr. Ahern's teaching
experience includes undergraduate and graduate biochemistry