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Breath from Salt


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Table of Contents



Part I
Chapter 1: Hello, Joey 1974
Chapter 2: The Treatment Plan 1974
Chapter 3: Case 44: Babies Hospital, New York City 1935
Chapter 4: A New Disease 1936-1937
Chapter 5: An Equal Opportunity Disease 1938-1942
Chapter 6: Christmas Homecoming 1974-1977
Chapter 7: The Sweat Test 1943-1960
Chapter 8: A Tribe of Desperate Parents 1950-1955
Chapter 9: Lessons from Polio 1955-1960
Chapter 10: The Registry 1960-1966
Chapter 11: The Therapist 1977
Chapter 12: A Disease in Search of Ideas 1964-1980
Chapter 13: The Hitman Cometh 1979-1982
Chapter 14: Salt and Water 1970-1981
Chapter 15: Salty Boy 1981-1983
Chapter 16: Birth of an Advocate 1984
Chapter 17: Out of Many, One 1978-1984

Part 2
Chapter 18: The Gene Hunters 1980-1984
Chapter 19: Lucky Number Seven 1984-1985
Chapter 20: Kate 1986
Chapter 21: To Screen or Not to Screen Newborns 1985
Chapter 22: Michigan 1985
Chapter 23: Joey's Long Goodbye 1986
Chapter 24: Mad Pursuit 1987
Chapter 25: The Gene 1989
Chapter 26: Runny, Like Water 1989-1994
Chapter 27: Venture Philanthropy-A New Way to Fund Drug Development 1977-1999
Chapter 28: The Gene Is the Medicine 1989-1991
Chapter 29: Transforming the Lungs 1992-2003
Chapter 30: First-in-Human Trials 1992-1993
Chapter 31: The Beall Curve 1996

Part 3
Chapter 32: The Joey Fund 1989-1999
Chapter 33: A Network for Developing Therapeutic Drugs 1997-1998
Chapter 34: Aurora 1998-1999
Chapter 35: The Gates Open 1987-2000
Chapter 36: A Tale of Four Families-CF in the New Millennium 1999
Chapter 37: The Takeover 2001
Chapter 38: Getting the Band Together 2001-2003
Chapter 39: Pay to Play 2002-2004
Chapter 40: Molecular Architects of Vertex West 2004-2005
Chapter 41: Rat to Man 2003-2004
Chapter 42: A Christmas Gift 2004-2005
Chapter 43: The Lucky Four 2005-2007
Chapter 44: The Doorman Launches the Era of Genetic Medicine 2007-2008
Chapter 45: Disruption Fall 2008
Chapter 46: Tasting like Average People 2010-2012
Chapter 47: Milestones to a Cure 2004-2015
Chapter 48: Tackling the Common Mutation 2004-2013
Chapter 49: What Mutation Are You? 2013-2014
Chapter 50: The Mother of All Deals 2014
Chapter 51: Very Personal Clinical Trials 2021-2017
Chapter 52: The Triple 2015-2017
Chapter 53: The Home Stretch 2018
Chapter 54: The Leftovers 2015-2020
Chapter 55: A New Generation 2017-2020

Epilogue 2019-2020

About the Author

About the Author

Bijal P. Trivedi is an award-winning freelance writer specializing in medicine and health. Her work has taken her from the hidden vaults of New York's Metropolitan Museum of Art to the Serengeti Plains to Moscow's Star City, where she blasted off with space tourism entrepreneurs on the "Vomit Comet" for astronaut training. Her work has appeared in Discover, Scientific American, New Scientist, Wired, The Economist, National Geographic, Science, Self, Nature, among others. Her feature "The Wipeout Gene" was anthologized in The Best American Science and Nature Writing: 2012. Trivedi is the former editor of the NIH Director's Blog, which shares compelling, cutting edge biomedical research with the general public. Trivedi also worked as a writer and editor for the National Geographic News Service, a wire service she helped launch in partnership with the New York Times Syndicate.


"I couldn't put the book down."

-Bill Gates

"A thorough and engrossing saga packed with information, Breath from Salt is really about the transformative power of hope. It arrives at just the right moment, when too many of us have forgotten what human faith, ingenuity, and relentless determination can accomplish."

-Dan Fagin, author of the Pulitzer Prize-winning Toms River

"Beautifully written, Breath from Salt brings to life the amazing story of a passionate community that dared to dream, work together, and take extraordinary risks to bring life-saving treatments to those with cystic fibrosis. Timely and important, the breakthroughs described in this book are likely to accelerate cures for many other genetic diseases."

-Dr. Preston W. Campbell, former president and CEO of the Cystic Fibrosis Foundation

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