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Catching Breath


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Table of Contents

1. Bringing the Dead Back to Life - Diagnosing TB in ancient remains 2. Growing Up Together- How Mycobacterium tuberculosis and Homo sapiens co-evolved 3. Populating the Planet- How TB spread around the world, and continues to do so today 4. Altered Evolution - How the human immune system has been shaped through natural selection by TB 5. Leaving Scars - TB doesn't induce natural immunity, so vaccination doesn't work 6. The Patient Pathogen - Mycobacterium tuberculosis can enter into a state of hibernation in the human lung 7. The Drugs Don't Work - How do you kill something that is barely alive? 8. Killing the Unkillable - New drugs for bad bugs 9. Third-world London - How TB is creeping in through the cracks 10. Pale and Beautiful - Changing attitudes towards TB 10. My Cat Infected Me with TB - TB in the news 11. The People Behind the Disease - Personal stories of TB survival and recovery 12. A Losing Battle? - How are we going to win the war against TB?

Promotional Information

Tuberculosis - an ancient disease, but not a disease of history. If we can understand the makings of TB, then maybe we can find a way to unmake it.

About the Author

Kathryn Lougheed worked in tuberculosis research for more than ten years, focusing on the biological mechanisms of latent tuberculosis. She completed her PhD at Imperial College London in 2006, before moving to the National Institute for Medical Research where she collaborated with industrial partners to develop inhibitors targeting Mycobacterium tuberculosis. Now a science writer, Catching Breath is her first book. @ilovebacteria / germzoo.blogspot.co.uk/


Lougheed captures the past 20 years or so of TB research with an insider's eye ... the fascinating pathogen and its deadly interactions with its host fuel Lougheed's book. Through her passion, many others may find inspiration. * Science *
An impressive survey. * New York Times Book Review *
Kathryn Lougheed gives an illuminating tour of TB past and present, explaining why it has once again become the world's leading infectious killer and describing the myriad reasons why we have still not defeated it. -- Mike Mandelbaum, Chief Executive, TB Alert
Tuberculosis is currently the leading cause of infectious deaths across the world and has proven difficult to address with drugs or vaccines. Kathryn Lougheed pulls back the curtain on this forgotten pandemic and reveals the biology of a pathogen that has achieved world domination in an engaging, accessible and yes, occasionally even humorous fashion. -- Sarah Fortune, MS, Professor of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health
Kathryn Lougheed conveys the excitement and frustrations of cutting edge research in a convivial and accessible manner that will delight and inform both specialist and non-specialist readers. -- Douglas B. Young, Fleming Professor of Medical Microbiology, Imperial College London

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