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Chronic Lung Disease in Early Infancy


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Table of Contents

Clinical Aspects

Historical Perspective: Early Observations and Subsequent Evolution of Bronchopulmonary Dysplasia
William H. Northway, Jr.
Epidemiology of Bronchopulmonary Dysplasia: Clinical Risk Factors and Associated Clinical Conditions
Alma Martinez, Peter Dargaville, and H. William Taeusch
Clinical Course and Lung Function Abnormalities During Development of Neonatal Chronic Lung Disease
Eduardo Bancalari and Alvaro Gonzalez
Radiographic Features of BPD and Potential Application of New Imaging Techniques
David K. Edwards and William H. Northway, Jr.
Pathology of Chronic Lung Disease of Early Infancy
Jacqueline J. Coalson
The Usefulness of Bronchoalveolar Lavage in Infants with Evolving Chronic Lung Disease
Carl W. White and Leland L. Fan
Inflammatory Mediators in Neonatal Lung Disease
Christian P. Speer and Peter Groneck
Infection in the Pathogenesis of Bronchopulmonary Dysplasia
William E. Benitz and Ann M. Arvin
Ventilation Strategies and Bronchopulmonary Dysplasia
W. Alan Hodson
Effect of Respiratory Care Practices on the Development of Bronchopulmonary Dysplasia
Michael R. Gomes and Thomas N. Hansen
Influence of Surfactant Replacement on Development of Bronchopulmonary Dysplasia
Alan H. Jobe
Drug Treatment for Established BPD
Thomas A. Hazinski
Nutritional Issues in Chronic Lung Disease of Premature Infants
Ilene R. S. Sosenko, Michael T. Kinter, and Robert J. Roberts
Pulmonary Function in BPD and Its Aftermath
Eric C. Eichenwald
Cardiovascular Abnormalities in Bronchopulmonary Dysplasia
Michael Apkon, Rodrigo Nehgme, and George Lister
Long-Term Recovery from Bronchopulmonary Dysplasia
Solomon Alkrinawi and Victor Chernick
The Goal: Prevention of BPD
Mildred T. Stahlman

Normal and Abnormal Alveolar and Airway Development

Unique Features of the Immature Lung that Make It Vulnerable to Injury
Scott H. Randell and Stephen L. Young
Hormonal Effects on Lung Maturation and Disease
Philip L. Ballard and Roberta A. Ballard
Mechanisms and Physiological Sequelae of Reactive Species Injury to the Alveolar Epithelium
Imad Y. Haddad, Sha Zhu, Samuel J. Tilden, and Sadid Matalon
Surfactant in Chronic Lung Injury
Richard J. King and Samuel Hagwood
The Regulation of the Formation of Pulmonary Alveoli
Donald J. Massaro and Gloria D. Massaro
Factors Mediating Cell Growth in Lung Injury
A. Keith Tanswell, Shilpa Buch, Mingyao Liu, and Martin Post
Developmental Airway Structure and Function in Health and Chronic Lung Injury
Howard B. Panitch and Thomas H. Shaffer

Normal and Abnormal Development of the Lung Circulation and Interstitium

Lung Development and the Effects of Chronic Hypoxia
Sheila G. Haworth
Altered Development of the Pulmonary Circulation in Chronic Lung Injury
Marlene Rabinovitch
Pulmonary Hypertension in Chronic Lung Disease of Infancy: Pathogenesis, Pathophysiology, and Treatment
Steven H. Abman
Connective Tissues in Lung Development and Diseases in Early Infancy
David J. Riley
Pulmonary Edema After Premature Birth: Progression from Acute to Chronic Lung Disease
Richard D. Bland and David P. Carlton

Mechanisms of Lung Injury and Repair During Development

Molecular Mechanisms of Oxygen-Induced Lung Injury
Charles Vincent Smith and Stephen E. Welty
Assessment of Tissue Injury from Reactive Oxygen Metabolites
Michael J. Thomas, Timothy W. Robison, and Henry Jay Forman
Chronic Lung Disease of Early Infancy: Role of Neutrophils
Diane E. Lorant, Kurt Albertine, and John F. Bohnsack
The Role of Pulmonary Macrophages in Chronic Lung Disease of Early Infancy
Michael P. Sherman and William E. Truog
Oxidants and Antioxidants: What Role Do They Play in Chronic Lung Disease
H. Lee Frank and Ilene R. S. Sosenko
Proteolytic Enzymes and Their Inhibitor in Lung Health and Disease
John R. Hoidal and Mari K. Hoidal
Site and Mechanism-Directed Interventions for Tissue Free Radical Injury
William R. Berrington, Margaret M. Tarpey, Bruce A. Freeman, and Bruce R. Pitt

Models of Lung Injury and Repair During Development

Genetic Models for the Study of Autocrine-Paracrine Signaling in Lung Development and Repair
Jeffrey A. Whitsett and Thomas R. Korfhagen
Animal Models of Chronic Lung Injury
Jacqueline J. Coalson, Steven R. Seidner, and Robert A. De Lemos


...describes the clinical, radiographic, and pathologic changes that have occurred since the discovery of bronchopulmonary dysplasia 30 years ago....highlights include...animal models that can be used to study the process of chronic lung disease through its evolution and during recovery.
"-Pulmonary Reviews

...an extensive and detailed review of bronchopulmonary dysplasia.
-Doody's Health Sciences Book Reviews

"...clearly written....
...an extremely valuable source of information for anyone who has an interest in the biology of lung....
...should be available in the library of any hospital.
"-Respiratory Care

"...valuable and well organized....
..should be an essential book for any chemist working in the area of solid state electrochemistry.
"-Journal of Solid State Electrochemistry

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