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DNA Topoisomerases

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Table of Contents

Preface... Table of Contents... Contributing Authors... 1- Type IA DNA Topoisomerases: A Universal Core and Multiple Activities Florence Garnier, Helene Debat, and Marc Nadal 2- Topoisomerase I and Genome Stability: The Good and The Bad Jang-Eun Cho and Sue Jinks-Robertson 3- DNA Topoisomerases as Targets for Antibacterial Agents Hiroshi Hiasa 4- DNA Supercoiling Measurement in Bacteria Yingting Liu, Zhi-Chun Hua, and Fenfei Leng 5- DNA Catenation Reveals the Dynamics of DNA Topology during Replication Alicia Castan, Pablo Hernandez, Dora B. Krimer, and Jorge B. Schvartzman 6- Mapping E. coli Topoisomerase IV Binding and Activity Sites Hafez El Sayyed and Olivier Espeli 7- The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling Fedor Kouzine, Laura Baranello, and David Levens 8- Immunoprecipitation of RNA:DNA Hybrids from Budding Yeast Aziz El Hage and David Tollervey 9- Detect ion of oriC-Independent Replication in Escherichia coli Cells Makisha Martel, Aurelien Balleydier, Julien Brochu, and Marc Drolet 10- Single-Molecule Magnetic Tweezer Analysis of Topoisomerases Kathryn H. Gunn, John F. Marko, and Alfonso Mondragon 11- Synthesis of Hemicatenanes for the Study of Type IA Topoisomerases Shun-Hsiao Lee, Tao-shih Hsieh, and Grace Ee-Lu Siaw 12- An Assay for Detecting RNA Topoisomerase Activity Muzammil Ahmad, Dongyi Xu, and Weidong Wang 13- Studying TDP1 Function in DNA Repair Shih-Chieh Chiang, Kirsty Liversidge, and Sherif F. El-Khamisy 14- Topoisomerase II Chromatin Immunoprecipitation Kayleigh A. Smith, Ian G. Cowell, and Caroline A. Austin 15- Analyzing Mitotic Chromosome Structural Defects after Topoisomerase II Inhibition or Mutation Juan F. Gimenez-Abian, Andrew B. Lane, and Duncan J. Clarke 16- Monitoring the DNA Topoisomerase II Checkpoint in Saccharomyces cerevisiae Katherine Furniss, Amit C. J. Vas, Andrew Lane, and Duncan J. Clarke 17- Studying Topoisomerase 1-Mediated Damage at Genomic Ribonucleotides Jessica S. Williams and Thomas A. Kunkel 18- A Fluorescence-Based Assay for Identification of Bacterial Topoisomerase I Poisons Thirunavukkarasu Annamalai, Bokun Cheng, and Yuk-Ching Tse-Dinh 19- Fluoroquinolone-Gyrase-DNA Cleaved Complexes Gan Luan and Karl Drlica 20- Detection of Topoisomerase Covalent Complexes in Eukaryotic Cells Jay Anand, Yilun Sun, Yang Zhao, Karin C. Nitiss, and John L. Nitiss 21- Visualization and Quantification of Topoisomerase-DNA Covalent Complexes Using the Trapped in Agarose Immunostaining (TARDIS) Assay Ian G. Cowell and Caroline A. Austin 22- Study of Plasmid-Mediated Quinolone Resistance in Bacteria George A. Jacoby

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