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The Exposome: a Primer


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The exposome is an emerging concept that hopes to address a systematic way to measure the influence of environmental exposures, measure the effects of life-long environmental exposures on health, and find how these exposures can influence disease

Table of Contents

1. The exposome: purpose, definition, and scope 2. When the genome falls short: limitations of a gene-centric view of health 3. Omic-based technologies and their impact on the exposome 4. The exposome in environmental health sciences and related disciplines 5. Managing and integrating exposome data: maps, models, computation, and systems biology 6. An exposome education: university and community-the practical exposome 7. Staging the exposome: a vision for international collaboration

About the Author

Gary W. Miller, PhD is the Vice Dean for Research Strategy and Innovation and Professor of Environmental Health Sciences at the Mailman School of Public Health at Columbia University. He was founding director of the HERCULES Exposome Research Center at Emory University, the first exposome-based center in the U.S. In addition to his work on the exposome, his research interests include the role of environmental factors in neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease, and the regulation of dopamine signaling in the brain. He served as Editor-in-Chief of Toxicological Sciences, the official journal of the Society of Toxicology, from 2013-2019.


"There is some suggestions for teaching the exposome, including an outline syllabus for a short course, and Miller's ideas about how the science might move forward over the next five to ten years... Overall I found this a useful introduction to the exposome and well worth reading if you want to better understand this new developing science." blog, January 2014

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