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Fundamentals of Biochemistry


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Table of Contents

PART I INTRODUCTION 1 Introduction to the Chemistry of Life 1 2 Water 22 PART II BIOMOLECULES 3 Nucleotides, Nucleic Acids, and Genetic Information 40 4 Amino Acids 76 5 Proteins: Primary Structure 93 6 Proteins: Three-Dimensional Structure 127 7 Protein Function: Myoglobin and Hemoglobin, Muscle Contraction, and Antibodies 176 8 Carbohydrates 217 9 Lipids and Biological Membranes 241 10 Membrane Transport 288 PART III ENZYMES 11 Enzymatic Catalysis 315 12 Enzyme Kinetics, Inhibition, and Control 355 13 Biochemical Signaling 396 PART IV METABOLISM 14 Introduction to Metabolism 436 15 Glucose Catabolism 472 16 Glycogen Metabolism and Gluconeogenesis 517 17 Citric Acid Cycle 551 18 Electron Transport and Oxidative Phosphorylation 581 19 Photosynthesis 623 20 Lipid Metabolism 657 21 Amino Acid Metabolism 712 22 Mammalian Fuel Metabolism: Integration and Regulation 767 PART V GENE EXPRESSION AND REPLICATION 23 Nucleotide Metabolism 793 24 Nucleic Acid Structure 821 25 DNA Replication, Repair, and Recombination 867 26 Transcription and RNA Processing 919 27 Protein Synthesis 962 28 Regulation of Gene Expression 1013 Solutions to Odd-Numbered Problems SP-1 Glossary G-1 Index I-1

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