The Early Earth.- Reconstructing the Universal Tree of Life.- The Nature of the Last Common Ancestor.- Ribozyme-Catalyzed Genetics.- The Scope of Selection.- The Evolutionary History of the Translation Machinery.- Functional Evolution of Ribosomes.- Aminoacyl-tRNA Synthetases as Clues to Establishment of the Genetic Code.- The Relation between Function, Structure and Evolution of Elongation Factors Tu.- Origin and Evolution of DNA and DNA Replication Machineries.- Early Evolution of DNA Repair Mechanisms.- Extant Variations in the Genetic Code.- Adaptive Evolution of the Genetic Code.- Expanding the Genetic Code in Vitro and in Vivo.

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