Basic Concepts. Ion Channel Methods. Ion Channel Families. Ion Channel Regulation. Ion Channel Physiology and Diseases. Index.
Jie Zheng, PhD, is a professor in the Department of Physiology and Membrane Biology at the University of California Davis School of Medicine. He earned a PhD in physiology from Yale University and received his postdoctoral training at the Howard Hughes Medical Institute (HHMI) and the University of Washington. Dr. Zheng has published over ten book chapters and review articles as well as numerous original research papers. His current research focuses on the activation mechanism of the temperature-dependent thermoTRP channels.
Matthew Trudeau, PhD, is an associate professor in the Department of Physiology at the University of Maryland School of Medicine. He earned a PhD in physiology from the University of Wisconsin-Madison and was a postdoctoral fellow at the University of Washington and the Howard Hughes Medical Institute (HHMI). Dr. Trudeau’s current work focuses on hERG potassium channels.
"… for several years now, researchers have discussed the need for a
new, updated, and modern standard work for the field particularly
given the explosion of new approaches to channel research, some of
which barely existed in 2001. And now we have it. Jie Zheng and
Matthew Trudeau have organized an authoritative multi-author
handbook covering much of the ion channel field, encompassing the
conceptual, technical, organizational, and pathophysiological
aspects of ion channel function … I enjoyed reading it and learned
a lot, particularly in areas that I haven’t kept up with. It will
be a great reference."
—Richard W. Aldrich, The Journal of General Physiology, July 2015"…
an excellent source to those wanting to understand, or better
understand, basic mechanisms and the diversity of ion channels with
respect to cellular function."
—The Physiologist, July 2015"This is the most comprehensive
reference book on ion channels to date. It covers from basic
concepts and mechanisms to advanced topics and applications. All
chapters are written by leading experts in their fields."
—Yongchang Chang, MD, PhD, Laboratory of Ion Channel Biophysics,
Division of Neurobiology, Barrow Neurological Institute"Today we
have single-channel recording, genes, hundreds of ion channel
subtypes, evolutionary trees, crystal structures, 300,000 papers,
many targeted drugs, and very many investigators contributing to
this vigorous and mainstream field. The chapters in this volume are
testimony to that beautiful success…"
—From the Foreword by Professor Bertil Hille, University of
Washington
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