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Hodges' Frontotemporal Dementia

Frontotemporal dementia (FTD) is a cruel disease, robbing patients of core human characteristics and wreaking havoc with relationships. Clinical and scientific interest in FTD and related disorders continues to grow rapidly, with major advances having occurred since this book's last publication. New clinical diagnostic criteria were published in 2011; new pathological discoveries have led to new diagnostic criteria; and major genetic discoveries have been made. This new edition covers these developments, providing the leading resource on FTD, PPA, PSP, CBD, FTD-ALS, and related disorders, now written by a more internationally representative group of authors than before. Providing an in-depth and expert synthesis of the status of our knowledge of FTD and related syndromes, the content includes chapters reviewing clinical, neuropsychiatric, neuropsychological, imaging, and other features of FTD and multidisciplinary approaches to patient management. Essential reading for specialist and generalist neurologists, psychiatrists, geriatricians, neuropsychologists, neuropathologists, and basic scientists in relevant fields.
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Table of Contents

List of contributors; Editor biographies; Foreword Bruce Miller; Preface; Part I. Introduction to and Brief History of FTD: 1. Historical introduction to FTD John Hodges; 2. Overview of the relationship of FTD to other neurodegenerative diseases Paul McMonagle and Andrew Kertesz; Part II. Clinical Phenotypes: 3. Overview of FTD and the variety of its clinical presentations Matthew Jones and David Neary; 4. Behavioral variant FTD Katya Rascovsky; 5. Primary Progressive Aphasia Chiara Cerami and Stefano F. Cappa; 6. The FTD-ALS spectrum Thomas H. Bak and Sharon Abrahams; 7. CBS/PSP Barbara Borroni and Antonella Alberici; Part III. Approach to the Diagnosis of FTD: 8. Overview of clinical assessment of frontotemporal dementia syndromes Bradford C. Dickerson, Simon Ducharme and Chiadi U. Onyike; 9. Neuropsychological assessment of FTD Teresa Torralva, Macarena Martinez Cuitino and Facundo Manes; 10. Imaging of FTD Jonathan D. Rohrer; 11. Biomarkers of FTD Nicolaas A. Verwey, Yolande A. L. Pijnenburg and Philip Scheltens; 12. Genetic counseling and testing Jill S. Goldman and Elizabeth McCarty Wood; Part IV. Pathology and Pathophysiology: 13. Neuropathology of FTD and related disorders Manuela Neumann, Gabor G. Kovacs and Ian R. A. Mackenzie; 14. Genetics of frontotemporal dementia and related disorders Marc Cruts and Christine Van Broeckhoven; 15. Pathophysiology and animal models of FTD Brian A. Warmus and Erik D. Roberson; Part V. Treatment: 16. The impact of FTD on daily life Claire O'Connor and Eneida Mioshi; 17. Practical management of FTD Ted Huey and Masood Manoochehri; 18. Current and future pharmacologic therapy of FTD and related disorders Richard M. Tsai and Adam L. Boxer; 19. Grassroots advocacy and patient/family education and support in FTD Susan Dickinson and Jill Shapira; Index.

About the Author

Bradford C. Dickerson, MD is an Associate Professor of Neurology, Harvard Medical School, and Director of the Frontotemporal Disorders Unit and Co-Investigator at the Alzheimer's Disease Research Center, Massachusetts General Hospital, Boston, MA, USA.

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