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Ion Channels in Health and Disease


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This concise, accessible book provides an overview of fundamental concepts in ion channels research to link defects in human disease

Table of Contents

1. Calcium channel auxiliary subunits in pain management 2. Sodium channels and pain 3. Voltage-gated ion channels in cancer 4. Novel channels regulating somatosensation 5. Ion channels in epilepsy 6. Skeletal myopathies caused by channelopathies 7. Endocrine disorders caused by channelopathies 8. Emerging roles of CaCC channels in health and disease 9. New roles for ion channels in neuropsychiatric disorders 10. Pharmacology and pathophysiology of calcium channels 11. Inherited cardiac arrhythmias 12. Ion channels and diabetes 13. Migraines and calcium channels 14. Immunity and ion channels

About the Author

Geoffrey S. Pitt is the Ida and Theo Rossi Distinguished Professor of Medicine at Weill Cornell Medicine and the Director of the Cardiovascular Research Institute. His current research investigates the structure, function and regulation ion channels and the disease that occur ("channelopathies") from abnormal ion channel function. His laboratory's use electrophysiology, biochemistry, structural biology, and animal models to discern how channelopathies cause diseases such as cardiac arrhythmias, epilepsy, autism, and ataxias.

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