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Lecture Notes


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Table of Contents

Preface to the Sixth Edition, v From the Preface to the First Edition, vi Key to symbols used in the figures, vii An overview of the immune system, viii Part 1 Immunity and the Immune System 1 The nature of immunity, 3 2 Immune recognition, 14 3 Lymphocyte development and activation, 30 4 Lymphocyte interactions, cytokines and the lymphoid system, 40 5 Immunoglobulins, 55 6 Complement, 69 7 Phagocytes, 76 8 Mast cells, basophils and eosinophils, 82 9 Killer cells, 89 Part 2 Immunopathology 10 Immunity and infection, 97 11 Primary and secondary immunodeficiency disorders, 112 12 The generation of tissue-damaging responses, 134 13 Mechanisms of immunological tissue damage, 153 14 Lymphoproliferative disease, 165 15 Transplantation, 177 16 Immunological therapy, 188 Part 3 Self-assessment Self-assessment questions, 199 Self-assessment answers, 209 Index, 215

About the Author

Ian Todd is at Queen's Medical Centre, Nottingham, UK Gavin Spickett is at Royal Victoria Infirmary, Newcastle UponTyne, UK


"For its price and size, it would be useful for most students, particularly in conjunction with lecture notes. Immunology is a rapidly changing discipline and this new edition is well justified." (Doody's, 30 September 2011) "Now in its 6th edition this book is an excellent introduction to core immunological knowledge as well as a revision text...This book should appeal to undergraduate and postgraduate students of medical, nursing and biological sciences." (G.J.Ebrahim, December 2010)

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