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MD Anderson Manual of Medical Oncology, Second Edition

State-of-the-art approaches to cancer management from the world's #1 oncology center The perfect clinical desk manual from the experts at MD Anderson Cancer Center Read the outstanding reviews of the previous edition: "As a detailed guide, [the book] offers practitioners a clear, user-friendly approach to the care of patients with cancer." -- New England Journal of Medicine "The portions of the text that summarize the chemotherapeutic literature are helpful and potentially useful to a busy medical oncologist. The graphic representations and flow charts are of high quality, are well designed and easy to follow, and are clinically useful. A number of good photographs have been provided that illustrate pathologic conditions...the Manual is well written, has extremely useful graphics, and represents a useful entry point for those interested in the management of malignant diseases." -- International Journal of Radiation Oncology, Biology, Physics "...[MD Anderson Manual of Medical Oncology] fulfills its goals of helping clinicians quickly evaluate therapeutic regimens and possibilities. Surgeons and radiation oncologists will find the text useful as a reference guide to what the medical oncologist can do and how the medical oncologist views their disciplines. The text is also of considerable help for physicians studying for board certification or recertification in medical oncology. Practicing medical oncologists would do well to have it in their personal libraries." -- Journal of the American Medical Association MD Anderson Manual of Medical Oncology offers clinicians an authoritative, easy-to-follow guide to the medical management of patients with cancer and its complications. Featuring concise but practical text and a large number of decision-making algorithms, the book gives physicians a current, templated approach to each disease and situation -- backed by the clincal expertise and authority of world recognized oncology researchers/practitioners. Key Features REVISED: competely updated coverage of the quickly evolving world of cancer therapeutics NEW: chapters include "Expert Commentary Sidebars" that provide clinical insights from leading subspecialists in radiation therapy, surgical oncology, pathology, and laboratory medicine NEW: brand new chapters on myelodysplasia, myeloproliferative diseases, and appendiceal cancer NEW: a brand new chapter on the important and underpublished topic of psycho-social issues in oncology Consistently formatted for a unified patient management strategy Packed with time-saving features, including The MD Anderson Work-Up Box and The MD Anderson Preferred Treatment Box
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Table of Contents

Contributors Preface Foreword PART I: LEUKEMIA 1. Acute Lymphoblastic Leukemia, Elias Jabbour, Amber Fullmer, Stefan Faderl 2. Adult Acute Myeloid Leukemia, Sameer A. Parikh, Elias Jabbour, Charles A. Koller 3. Chronic Lymphocytic Leukemia and Associated Disorders, Ravin J. Garg, Carlos Bueso-Ramos, Susan O'Brien 4. Chronic Myeloid Leukemia, Naveen Pemmaraju, Sameer A. Parikh, Elias Jabbour, Hagop M. Kantarjian, Jorge Cortes 5. Myelodysplastic Syndromes: The MD Anderson Cancer Center Approach, William S. Stevenson, Carlos Bueso-Ramos, Guillermo Garcia-Manero 6. Philadelphia Chromosome-Negative Myeloproliferative Neoplasms, Nitin Jain, Hesham M. Amin, Srdan Verstovsek PART II: LYMPHOMA AND MYELOMA 7. The Indolent Lymphomas, Peter McLaughlin, Nathan Fowler, Nini Liu, L. Jeffrey Medeiros 8. Aggressive and Highly Aggressive B-cell Lymphomas, Luis E. Fayad, Sergej Konoplev, Hubert H. Chuang, M. Alma Rodriguez; Commentary: Bouthaina S. Dabaja 9. T-cell Lymphomas, Jenny Pozadzides, Madeleine Duvic, Barbara Pro 10. Hodgkin Lymphoma, Jason Westin, Fredrick B. Hagemeister, Valerie K. Reed, Michelle Fanale 11. Multiple Myeloma and Other Plasma Cell Dyscrasias, Tiffany P. Avery, Nina Shah, Weijun Fu, Donna M. Weber, Gary Lu, Pei Lin, Muzaffar H. Qazilbash, Michael Wong PART III: STEM CELL TRANSPLANTATION 12. Allogeneic Transplantation, Carrie Yuen, Sergio Giralt 13. Autologous Stem Cell Transplantation, Carrie Yuen, Richard E. Champlin PART IV: LUNG CANCER 14. Small Cell Carcinoma of the Lungs, Kathryn A. Gold, Bonnie S. Glisson; Commentary:Cesar Moran 15. Non-small Cell Lung Cancer, Don Gibbons, Katherine M. Pisters, Faye Johnson; Commentary: George A. Eapen PART V: HEAD AND NECK CANCER 16. Head and Neck Cancer, Eric S. Kim, G. Brandon Gunn, William Nassib William Jr., Merrill S. Kies PART VI: GASTROINTESTINAL CARCINOMAS 17. Gastric and Esophageal Cancer, Alexandria T. Phan 18. Pancreatic Cancer, Rachna T. Shroff, Robert A. Wolff, Milind M. Javle 19. Hepatobiliary Malignancies, Nishin A. Bhadkamkar, Milind M. Javle, Rony Avritscher, Sunil Krishnan, Ahmed O. Kaseb 20. Small Bowel Cancer and Appendiceal Tumors, Michael J. Overman, Christopher Lieu; Commentary: Keith F. Fournier 21. Colorectal Cancer, Nishin Bhadkamkar, Christopher H. Crane, Miguel Rodriguez-Bigas; Scott Kopetz; Cathy Eng 22. Anal Cancer, Tzu-chuan Jane Huang, Cathy Eng; Commentary: Christopher H. Crane 23. Neuroendocrine Tumors, John Andrew Jakob, Carlo M. Contreras, Bruno C. Odisio, Sanjay Gupta, Eddie K. Abdalla, James C. Yao PART VII: BREAST CANCER 24. Early-Stage and Locally Advanced Breast Cancer, Sapna P. Patel, Aman U. Buzdar; Commentary: Kelly K. Hunt 25. Metastatic Breast Cancer, Mariana Chavez-MacGregor, Vicente Valero 26. Inflammatory Breast Cancer, Windy Marie Dean-Columb, Massimo Cristofanilli 27. Special Situations in Breast Cancer, Rachel L. Theriault, Karin M.E. Hahn PART VIII: GYNECOLOGIC MALIGNANCIES 28. Ovarian Cancer, Bryan T. Hennessy, Grace K. Suh, Maurie Markman 29. Tumors of the Uterine Corpus, Grace K. Suh, Bryan T. Hennessy, Maurie Markman 30. Tumors of the Uterine Cervix, Pedro T. Ramirez, Maria Jimena Lange, John J. Kavanagh, Alexandria T. Phan, Siriwan Tangjitgamol 31. Gestational Trophoblastic Tumors, Maurie Markman, John J. Kavanagh PART IX: GENITOURINARY CARCINOMA 32. Renal Cell Carcinoma, Eric Jonasch, Surena F. Matin, Lance C. Pagliaro, Christopher G. Wood, Nizar M. Tannir 33. Bladder Cancer, Arlene O. Siefker-Radtke, Colin P.N. Dinney, Dogdan A. Czerniak, Randall E. Millikan; Commentary: David J. McConkey 34. Prostate Cancer, Paul Corn, Christopher Logothetis 35. Penile Cancer, Lance C. Pagliaro 36. Germ Cell Tumors, Heather D. Brooks, Lance C. Pagliaro, Zita Dubauskas Lim, Louis L. Pisters, Nizar M. Tannir PART X: MISCELLANEOUS TUMORS 37. Tumors of the Central Nervous System, Nicole A. Shonka, Sigmund H. Hsu, W.K. Alfred Yung; Commentary: Anita Mahajan, Sujit Prabhu 38. Endocrine Malignancies, Naifa Lamki Busaidy, Mouhammed Amir Habra, Rena Vassilopoulou-Sellin 39. Malignant Melanoma, Kevin B. Kim, Michael A. Davies, Ronald P. Rapini, Patrick Hwu, Agop Y. Bedikian 40. Soft Tissue and Bone Sarcomas, Anthony Conley, Min S. Park, Jonathan C. Trent, Shreyaskumar Patel 41. The AIDS-related Cancers, Adan Rios, Fredrick B. Hagemeister 42. Carcinoma of Unknown Primary, Gauri R. Varadhachary PART XI: SUPPORTIVE CARE 43. Infection in the Neutropenic Patient, Kenneth V.I. Rolston 44. Fungal and Viral Infections in Cancer Patients, Bruno P. Granwehr, Roy F. Chemaly, Dimitrios P. Kontoyiannis; Commentary: Jeffrey J. Tarrand 45. Endocrine and Metabolic Complications of Cancer Therapy, Mouhammed Amir Habra, Naifa Lamki Busaidy, Sai-Ching Jim Yeung, Rena Vassilopoulou-Sellin 46. Oncologic Emergencies, Sai-Ching Jim Yeung, Ellen F. Manzullo PART XII: PALLIATIVE CARE AND SYMPTOM MANAGEMENT 47. Defining Palliative Care in Oncology, Jessica Masterson, Michael J. Fisch; Commentary: Jeffrey E. Lee 48. Pain Management and Symptom Control, Suresh K. Reddy, Gabriel Lopez, Ahmed Elsayem PART XIII: LONG-TERM SURVIVAL 49. Pediatric Long-Term Follow-up, Joann I. Ater, Norman Jaffe, Nita R. Burrer 50. Adult Long-Term Follow-up, Pamela N. Schultz, Charles J. Stava, Mouhammad Amir Habra, Rena Vassilopoulou-Sellin 51. Rehabilitation, Jack Fu, Ki Y. Shin Index

About the Author

Hagop M. Kantarjian, MD Professor of Medicine Chair, Department of Leukemia The University of Texas MD Anderson Cancer Center Houston, TX Robert A. Wolff, MD Professor of Medicine Department of Gastrointestinal Medical Oncology The University of Texas MD Anderson Cancer Center Houston, TX Charles A. Koller, MD Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center Houston, TX

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