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This is the first work to take a comprehensive look at the application of Magnetic Resonance (MR) techniques in the diagnosis, follow-up and therapy monitoring of dementing illnesses. The authors present an overview of MR findings in neurodegenerative and vascular disorders leading to dementia. In doing so, they also discuss other diseases that lead to cognitive and/or behavioural deterioration, such as infectious inflammatory disorders, toxic encephalopathies, inborn errors of metabolism of adult onset and post-traumatic, post-radiotherapy and post-chemotherapy conditions. This authoritative, well-written and richly illustrated reference work is indispensable for anybody working in the field.
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Table of Contents

Introduction. Brain atrophy and normal aging.- MR applications in dementia. MR techniques. Image processing.- Neurodegenerative disorders. Alzheimer's disease. Dementia with Lewy bodies. Frontotemporal lobar degeneration. Dementia with Parkinsonism. Huntington's dementia. Progressive subcortical gliosis. Prion-linked dementias.- Disorders primarily affecting white matter. Viral infections leading to dementia. Inflammatory disorders. Inborn errors of metabolism. Toxic-allergic encephalopathies. Dementia after trauma, irradiation, chemotherapy and infection.- Vascular dementias. Commonly used criteria for vascular dementia. Vascular dementia: MR features of subgroups. Vascular dementias with characteristic clinical course, familial story, pathophysiology and MR pattern. Systemic disorders and cerebrovascular disease. Vasculitis.- Miscellaneous forms of dementia. Normal pressure hydrocephalus and dementia. Intra- and extra-axial tumors and dementia. Idiopathic calcinosis of Fahr.

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Reviews

From the reviews: "This is a well written and beautifully illustrated book which has the ambitious aim of illustrating `the role of MRI in diagnosis, follow-up, therapy monitoring and research on dementia in all its manifestations'. The text is well written, illustrated and laid out and is comprehensive in its scope. ... this is an excellent book, both as reference text for specific diseases and as a general overview of dementia and its imaging. It is highly recommended to neuroradiologist, neurologists, psychiatrists, neurosurgeons and others ... ." (British Journal of Neurosurgery, Vol. 17 (6), 2003) "This book is relevant to anyone interested in the care of patients with dementia ... . The MRI illustrations are lavish and of high quality ... . References are to be found at the end of each subsection and are comprehensive and up to date. The index is good. ... This is an interesting, very readable book with excellent coverage of its subject. It is recommended reading for any individuals interested in this field." (S. Barker, Neuroradiology, Vol. 45 (8), 2003) "The idea behind this book was to bring together clinical, genetical, pathologic and radiological information, as well as historical details, research perspectives and therapeutic suggestions, in order to provide a comprehensive view of the many disorders that lead to dementia. ... The quality of the illustrations is excellent with many color figures of histological specimens, PET studies and diagrams. ... It should be present in every neuroradiological department. ... this new publication will become a standard reference book." (M. Savoiardo, European Radiology, Vol. 13 (4), 2003) "The frequent use of several figures on almost every page - with more than 900 original high-quality figures - helps to organize the material and to illustrate the content of the text. ... The information is made clear and is accurate. The target audience is neurologists, psychiatrists, geriatricians, and radiologists. The length of the book and its level of details make it ideal for both residents looking for a practical knowledge on this subject and trained specialists." (Didier Leys, European Neurology, Vol. 48 (4), 2002) "The authors ... present an extremely useful, readable, and well-structured reference book for radiologists, geriatricians, neurologists, and psychiatrists who have to deal with dementia patients. ... The clearly structured, highly didactical presentation of the various diseases makes it also a textbook for beginners in the field. ... The carefully selected and well-presented magnetic resonance images do not only illustrate well the cases in point, but make reading the book also an intellectual and an aesthetic pleasure. It can be highly recommended ... ." (H.B. Stahelin, Gerontology, Vol. 48 (6), 2002)

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