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Mechanics of the Circulation

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Preface.- 1. How do crossbridges produce the sliding force between actin and myosin filaments in muscle.- 2. Stepwise shortening and the mechanism of msucle contraction.- 3. Mechanics of the myofibril.- Discussion.- 4. Excitation-contraction coupling in myocardium: Implications of calcium release and Na/Ca exchange.- 5. Calcium influx and sarcoplasmic reticulum calcium release in cardiac excitation contraction coupling.- Discussion.- 6. Cardiac energetics.- 7. Energetics of the heart.- Discussion.- 8. On the force-length relation in myocardium.- 9. Segment length mechanics of cardiac muscle.- Discussion.- 10. Regulation of the actin-myosin interaction by calcium; the troponin tropomyosin complex.- 11. Evidence that a decrease in sarcomere length reduces the affinity of troponin in the intact cardiac myofibril.- Discussion.- 12. Mechanics of cardiac contraction and the phosphorylation of sarcotubular and myofilament proteins.- Discussion.- 13. Ventricular pump function and arterial resistance.- 14. Ventricular wall motion.- Discussion.- 15. Mechanics of the ventricular septum.- 16. Mechanics of the interventricular septum.- Discussion.- 17. On the interaction between the pericardium and the heart.- 18. The mechanical effects of the pericardium on the left ventricle.- Discussion.- 19. Role of a changing venous capacitance in cardiovascular homeostasis.- 20. Role of a changing venous capacitance in cardiovascular homeostasis.- Discussion.- 21. Principles of arterial hemodynamics.- 22. Arterial dynamics: a comment on arterial wave reflections.- Discussion.- 23. Control of the circulation.

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