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Molecular Genetic Testing in Surgical Pathology
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Table of Contents

1 Structure and Function of DNA and RNA 1 2 DNA Damage, Mutations, and Repair 29 3 Cytogenetics 58 4 Fluorescence in situ Hybridization 72 5 Polymerase Chain Reaction 86 6 Nucleic Acid Electrophoresis and Hybridization 111 7 DNA Sequence Analysis 123 8 Sensitivity and Specificity Issues 140 9 Microarrays 152 10 Clinical Testing of Patient's Specimens 171 11 Tumors of Soft Tissue and Bone 186 12 Endocrine System 232 13 Molecular Diagnostics in Hematopathology 250 14 Neural Tumors and Neuromuscular Diseases 275 15 Gastrointestinal Tract 294 16 Reproductive Organs 322 17 Urinary Tract 345 18 Skin 367 19 Lung and Mediastinum 380 20 Breast 401 21 Head and Neck 415 22 Infectious Diseases 426 23 Identity Determination 440 24 The Future 451 Appendix 1 Genetic Codes 459 Appendix 2 Amino Acids 461 Appendix 3 Summary of Recommended Nomenclature for Describing Mutations 462 Subject Index 464

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