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Nuclear Signaling Pathways and Targeting Transcription in Cancer
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Preface.- Steroid Receptor Coactivators (SRCs) as Integrators of Multiple Signaling Pathways in Cancer Progression.- Role of Alteration/Deficiency in Activation (ADA) Complex in the Cell Cycle, Genomic Instability and Cancer.- RUNX2 Transcriptional Regulation in Development and Disease.- Epigenetic Mechanisms of Cancer Metastasis.- Regulatory Effects of Arsenic on Cellular Signaling Pathways: Biological Effects and Therapeutic Implications.- Nuclear Factors Linking Cancer and Inflammation.- Regulation of the Jak/STATs Pathways by Histone Deacetylases.- Receptor Tyrosine Kinases in the Nucleus: Nuclear Functions and Therapeutic Implications in Cancers.- Nucleolar Signaling Determines Cell Fate – The RP-Mdm2-p53 Axis Fine-Tunes Cellular Homeostasis.- Transcriptional Regulation of Lipogenesis as a Therapeutic Target for Cancer Treatment.- Selective Inhibition of Acetyl-Lysine Effector Domains of the Bromodomain Family in Oncology.- Domain Specific Targeting of Cancer.- The Potential of Targeting Splicing for Cancer Therapy.- Exploiting Cell Cycle Pathways in Cancer Therapy: New (and Old) Targets and Potential Strategies.- Histone Demethylases in Prostate Cancer.- Therapeutic Significance of Chromatin Remodeling Complexes in Cancer.- Index.

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