Download the Free Fishpond App!
Download on the App Store

Android App on Google play
Nucleosides and Nucleotides as Antitumor and Antiviral Agents

Already own it?

Sell Yours
Home » Books » Science » Medicine » Pharmacology

Nucleosides and Nucleotides as Antitumor and Antiviral Agents

By D. C. Baker (Edited by), Chung K. Chu (Edited by)

Elsewhere $187 $149   Save $38.00 (20%)
or 4 easy payments of $37.25 with What's this?
Free shipping Australia wide
Ships from UK
Order Now for Christmas with e-Gift
Register or sign-in to rate and get recommendations.
Format: Paperback, 336 pages, 1993 Edition
Other Information: 18 black & white illustrations, biography
Published In: United States, 21 October 2012
Due to the worldwide epidemic of acquired immunodeficiency syndrome (AIDS), the past ten years have witnessed a flurry of activity in the chemotherapy of viral diseases. Unprecedented scientific efforts have been made by scientists and clinicians to combat infections of human immunodeficiency virus (HIY), the causative agent. Looking back over the past ten years, we have made remarkable progress toward the treatment of the viral disease: isolation of HIV only two years after the identification of the disease, plus major strides in the areas of the molecular biology and virology of the retrovirus, etc. More remarkably, the discovery of the chemotherapeutic agent AZT (Retrovir) was made within two years after the isolation and identification of the virus, followed by unprecedented drug development efforts to culminate in the FDA approval of AZT in twenty-three months, which was a record-breaking time for approval of any drug for a major disease. The last six to seven years have particularly been an exciting and productive period for nucleoside chemists. Since the activity of AZI' was established in 1985, nucleoside chemists have had golden opportunities to discover additional anti-HIV nucleosipes, which are hoped to be less toxic and more effective than AZT, and the opportunity continues. As we all are aware, AZT possesses extremely potent anti-HIY activity, and no other nucleoside or non- nucleoside has surpassed the potency of AZT in vitro.

Table of Contents

Design of New Types of Antitumor Nucleosides (A. Matsuda et al.). Lithiation Chemistry of Uridine Derivatives (H. Tanaka et al.). A Synthesis of 2'Fluoro and 3'FluoroSubstituted Purine Nucleosides via a Direct Approach (K.W. Pankiewicz, K.A. Wantanabe). Allenols Derived from Nucleic Acid Bases-A New Class of AntiHIV Agents (J. Zemlicka). StructureActivity Relationships among HIV Inhibatory, 4'Substituted Nucleosides (E.J. Prisbe et al.). Approaches to Novel Isomeric Nucleosides as Antiviral Agents (V. Nair). Carbocyclic 7Deazaguanosine Nucleosides as Antiviral Agents (S.W. Schneller et al.). Synthesis and Anticancer and Antiviral Activity of Certain Pyramidine Nucleoside Analogues (T.S. Lin, M.C. Liu). Stereocontrolled Routes for the Synthesis of AntiHIV and AntiHBV Nucleosides (J.W. Beach et al.). 5Substituted Arabinofuranosyluracil Nucleosides as Antiherpes Agents (H. Machida, S. Sakata). 6 additional articles. Index.

Promotional Information

Springer Book Archives

EAN: 9781461362210
ISBN: 1461362210
Publisher: Springer-Verlag New York Inc.
Dimensions: 25.4 x 17.78 x 1.85 centimetres (0.66 kg)
Age Range: 15+ years
Tell a friend

Their Email:

Sell Yours

Already own this item?
Sell Yours and earn some cash. It's fast and free to list! (Learn More.)

Review this Product


Related Searches


Webmasters, Bloggers & Website Owners

You can earn a 5% commission by selling Nucleosides and Nucleotides as Antitumor and Antiviral Agents on your website. It's easy to get started - we will give you example code. After you're set-up, your website can earn you money while you work, play or even sleep!



Are you the Author/Publisher? Improve sales by submitting additional information on this title.


This item ships from and is sold by Fishpond World Ltd.