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Nutrition and Brain Development


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Table of Contents

1. Cellular Makeup of the Brain.- 1.1. Neuron.- 1.2. Neuroglia.- 2. Growth Characteristics of the Brain.- 2.1. Physical and Cellular Growth.- 2.2. Biochemical Parameters of Brain Growth.- 2.3. Morphological Changes.- 3. Energy Source.- 3.1. Glucose.- 3.2. Alternate Source of Energy (Ketone Bodies).- 4. Blood-Brain Barrier System.- 4.1. Early Studies.- 4.2. Transport of Lipids from Blood into the Brain.- 4.3. Nonmorphological Nature of the Blood-Brain Barrier System.- 5. Alcohol: Effects on the Central Nervous System.- 5.1. Effects on the Adult.- 5.2. Effects of Alcohol on the Fetus: Fetal Alcohol Syndrome.- 6. Effects of Malnutrition on Brain Development.- 6.1. Caloric Insufficiency (Human Studies).- 6.2. Animal Studies.- 6.3. Effect of Protein Deficiency.- 6.4. Effect of Fat Deficiency.- 6.5. Effect of Trans Fatty Acids.- 6.6. Role of Carbohydrates in Brain Development.- 6.7. Hypoglycemia.- 6.8. Hexoses Other Than Glucose.- 6.9. Polysaccharides: Glycogen.- 6.10. Effect of Starvation.- 7. Vitamin Deficiencies and Excesses.- 7.1. Introduction.- 7.2. Thiamine Deficiency.- 7.3. Vitamin B2 (Riboflavin) Deficiency.- 7.4. Nicotinic Acid (Niacin) Deficiency.- 7.5. Vitamin B6 (Pyridoxine) Deficiency.- 7.6. Folic Acid Deficiency.- 7.7. Vitamin B12 Deficiency.- 7.8. Biotin.- 7.9. Pantothenic Acid Deficiency.- 7.10. Choline Deficiency.- 7.11. Vitamin A (Retinol, Retinal, and Retinoic Acid).- 7.12. Vitamin E (Tocopherols).- 7.13. Vitamin D.- 8. Mineral Deficiencies and Excesses.- 8.1. Zinc.- 8.2. Copper.- 8.3. Mercury.- 8.4. Lead.- 8.5. Aluminum.- 8.6. Cadmium.- 9. Nutrition and Neurotransmitters.- 9.1. Introduction.- 9.2. Signal Transmission.- 9.3. Dopamine.- 9.4. Serotonin.- 9.5. Catabolism of Neurotransmitters: Monoamine Oxidase.- 10. Neuropeptides.- 10.1. Introduction.- 10.2. Substance P.- 10.3. Enkephalins.- 10.4. Endorphins.- 10.5. Nutritional Significance.- 11. Inborn Errors of Metabolism.- 11.1. Lipodoses.- 11.2. Phenylketonuria.- 11.3. Maple Syrup Urine Disease.- References.

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