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The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology


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1. Overview of Diagnostic Terminology and Reporting2. Category I. Non-Diagnostic3. Category II. Negative (for Malignancy)* Acute Pancreatitis* Chronic Pancreatitis* Autoimmune Pancreatitis* Pseudocyst* Lymphoepithelial Cyst* Splenule/Accessory Spleen4. Category III. Atypical5. Category IV: Neoplastic: Benign* Serous Cystadenoma* Neuroendocrine Microadenoma* Lymphangioma

6. Category IV: Neoplastic: Other* Pancreatic Neuroendocrine Tumor* Solid-Pseudopapillary Neoplasm* Neoplastic Mucinous Cysts (Intraductal papillary mucinous neoplasm (IPMN) and Mucinous cystic neoplasm (MCN)7. Category V. Suspicious (for Malignancy)8. Category VI. Positive or Malignant* Ductal adenocarcinoma and variants* Acinar Cell Carcinoma* High-grade neuroendocrine carcinoma* Pancreatoblastoma* Lymphoma* MetastasesAppendix A: Template for Cyst DiagnosisAppendix B: Mucinous EtiologyAppendix C: Useful Ancillary Tests

About the Author

Martha Bishop Pitman, MDDepartment of PathologyMassachusetts General HospitalBoston, MAUSALester J. Layfield, MDDepartment of Pathology and Anatomical SciencesUniversity of Missouri Medical CenterColumbia, MOUSA

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