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This book describes a novel and proven approach to cytologically classify urinary samples for the detection of bladder cancer and lesions of the upper urinary tract. The new method is based on the collective experience of knowledgeable cytopathologists who have tested the terminology within their own laboratories for reproducibility and predictability of neoplasms of the urinary tract. Accompanying the written criteria for each diagnostic category are meticulously photographed exemplars of the cellular features, with cogently annotated descriptions of the photographs. The book thereby performs as an atlas for microscopists involved in diagnostic cytopathology at all levels of their education. Included in the targeted readership are experienced pathologists, cytotechnologists, and students of both professional groups. The new terminology also considers the clinical aspects of patient management. Written by experts in the field who convened at the 18th International Congress of Cytology in Paris, The Paris System for Reporting Urinary Cytology presents a global standard for reporting and a new philosophic approach that maximizes the strengths of detecting the potentially lethal high grade lesions by urinary cytology, and recognizes without apology the inability to reliably detect the low grade lesions in urinary cytology. The Concept has been endorsed by the American Society Of Cytopathology, and the International Academy of Cytology.
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Table of Contents

Chapter 1 Pathogenesis of Urothelial CarcinomaEva M. Wojcik and Stefan E. PambuccianChapter 2Adequacy of Urine Specimens (Adequacy)Matthew T. Olson (Chair), Guliz A. Barkan, Monique Courtade-Saidi, Z. Laura Tabatabai, Yuji Tokuda, Toyonori Tsuzuki, and Christopher J. VandenBusscheChapter 3Negative for High Grade Urothelial Carcinoma (Negative)Dorothy L. Rosenthal (Chair), Michael B. Cohen, Hui Guan, Christopher L. Owens, Yuji Tokuda, and Eva M. WojcikChapter 4Atypical Urothelial Cells (AUC) Guliz A. Barkan (Chair), Tarik M. Elsheikh, Daniel F. I. Kurtycz, Sachiko Minamiguchi, Hiroshi Ohtani, Eric Piaton, Spasenija Savic Prince, Z. Laura Tabatabai, and Christopher J. VandenBusscheChapter 5Suspicious for High Grade Urothelial Carcinoma (Suspicious) Fadi Brimo (Chair), Manon Auger, Tarik M. Elsheikh, Hui Guan, Mitsuru Kinjo, Eric Piaton, Dorothy L. Rosenthal, Tatsuro Shimokama, and Rosemary H. TambouretChapter 6 High Grade Urothelial Carcinoma (HGUC)Momin T. Siddiqui (Chair), Guido Fadda, Jee-Young Han, Christopher L. Owens, Z. Laura Tabatabai, and Toyonori TsuzukiChapter 7Low Grade Urothelial Neoplasia (LGUN)Eva M. Wojcik (Chair), Tatjana Antic, Ashish Chandra, Michael B. Cohen, Zulfia McCroskey, Jae Y. Ro, and Taizo ShiraishChapter 8 Other Malignancies Primary and Metastatic and Miscellaneous LesionsRana S. Hoda (Chair), Stefan E. Pambuccian, Jae Y. Ro, and Sun Hee SungChapter 9Ancillary Studies in Urinary CytologyLukas Bubendorf (Chair), Nancy P. Caraway, Andrew H. Fischer, Ruth L. Katz, Matthew T. Olson, Fernando Schmitt, Margareta Strojan Flezar, Theodorus H. Van Der Kwast, and Philippe VielhChapter 10Cytopreparatory TechniquesGary Gill (Chair), William N. Crabtree, and Deidra P. KellyChapter 11Clinical Management, Including Microscopic Hematuria Marcus L. Quek (Chair), Trinity J. Bivalacqua, Ashish M. Kamat, and Mark P. Schoenberg

About the Author

Dorothy L. Rosenthal, MDProfessor of Pathology, Oncology & Gynecology/Obstetrics, The Johns Hopkins University, The Johns Hopkins Hospital, Department of Pathology/Cytopathology, Baltimore, MD, USAEva M. Wojcik, MDChair of Pathology, Helen M. and Raymond M. Galvin Professor Pathology & Urology, Loyola University Medical Center, Department of Pathology, Maywood, IL, USADaniel F. I. Kurtycz, MD Medical Director, Wisconsin State Laboratory of Hygiene Professor, University of Wisconsin Hospitals & Clinics, Department of Pathology and Laboratory Medicine, Madison WI, USA


"Standardization to aid the clinical decision making process is essential and the Paris system provides a basis for both the pathologist and the clinician. The use of defined criteria and abundant photomicrographs in this book are a definite asset to this reporting system and provide strong scaffolding for future revisions as more data becomes available. This book will be very useful to cytopathology laboratories as they adapt to this reporting system." (Brenda J. Sweeney, The ASC Bulletin, Vol. LIV (1), January, 2017)"This book presents the standardized reporting system and nomenclature for urine cytopathology ... . The audience is pathologists and resident trainees who regularly practice cytopathology. Urologists and oncologists also will find the book useful in clinical practice. ... This is an excellent contribution to the cytology literature and should be in any cytologist's library. The illustrations are excellent and can assist pathologists when encountering difficult cases. ... Overall, this will make an excellent addition to departmental and pathologists' libraries." (Kyle D. Perry, Doody's Book Reviews, May, 2016)

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