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Phage and the Origins of Molecular Biology


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Note from the Publisher Preface to the First Edition John Cairns, Gunther S. Stent, James D. Watson Preface to the Expanded Edition John Cairns I. ORIGINS OF MOLECULAR BIOLOGY Introduction: Waiting for the Paradox Gunther S. Stent A Physicist Looks at Biology Max Delbr fc;ck Biochemical Genetics: Some Recollections George W. Beadle The Target Theory K.G. Zimmer High Energy Phosphate Bonds: Optional or Obligatory? Herman M. Kalckar II. THE PHAGE RENAISSANCE Bacteriophage: One-Step Growth Emory L. Ellis Electron Microscopy of Phages Thomas F. Anderson The Eclipse in the Bacteriophage Life Cycle A.H. Doermann The Prophage and I Andr e9; Lwoff The Injection of DNA into Cells by Phage A.D. Hershey Transfer of Parental Material to Progeny Lloyd M. Kozloff Electron Microscopy of Developing Bacteriophage Edward Kellenberger III. PHAGE GENETICS Phenotypic Mixing Aaron Novick Mating Theory N. Visconti On the Physical Basis of Genetic Structure in Bacteriophage A.D. Kaiser Adventures in the rII Region Seymour Benzer Conditional Lethals R.S. Edgar IV. BACTERIAL GENETICS Mutations of Bacteria and of Bacteriophage S.E. Luria Gene, Transforming Principle, and DNA Rollin D. Hotchkiss Sexual Differentiation in Bacteria William Hayes Bacterial Conjugation Elie L. Wollman Story and Structure of the bb; Transducing Phage J. Weigle V. DNA Growing Up in the Phage Group J.D. Watson Demonstration of the Semiconservative Mode of DNA Duplication Matthew Meselson and Franklin W. Stahl The Autoradiography of DNA John Cairns a6;x: Multum in Parvo Robert L. Sinsheimer The Relation between Nuclear and Cellular Division in Escherichia coli Ole Maal f8;e VI. RAMIFICATIONS OF MOLECULAR BIOLOGY The Mammalian Cell T.T. Puck The Plaque Technique and the Development of Quantitative Animal Virology Renato Dulbecco Quantitatitve Tumor Virology H. Rubin The Natural Selection Theory of Antibody Formation; Ten Years Later Niels K. Jerne Cybernetics of the Insect Optomotor Response Werner E. Reichardt Teminal Redundancy, or All's Well that Ends Well George Streisinger VII. REPRINTS How Molecular Biology Started John C. Kendrew Reprinted from Scientific American, March 1967 That Was the Molecular Biology That Was Gunther S. Stent Reprinted from Science, April 26, 1968 Max Delbr fc;ck, 1906-1981 Gunther S. Stent Reprinted from Genetics, May 1982 Timeline Photo Gallery


There are those who cherish first editions, but the centennial edition, which contains everything in earlier versions, has a bonus beyond the inclusion of the gallery of photographs - it is cheaper than most of its well-worn predecessors. I heartily recommend the book to those who have never read these personal narratives of the early days of microbial genetics. All can benefit and learn from Phage and the Origins of Molecular Biology. Molecular biology is not dead! Long live the phage!" The Quarterly Review of Biology

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