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Practical Transfusion Medicine

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Table of Contents

List of contributors, ix Preface to the Fourth Edition, xvi 1 Introduction: recent evolution of transfusion medicine, 1 Paul M. Ness Part One: Basic Principles of Immunohaematology 2 Essential immunology for transfusion medicine, 11 Jaap Jan Zwaginga & S. Marieke van Ham 3 Human blood group systems, 21 Geoff Daniels 4 Human leucocyte antigens, 31 Cristina V. Navarrete 5 Platelet and neutrophil antigens, 45 David L. Allen, Geoffrey F. Lucas & Michael F. Murphy Part Two: Complications of Transfusions 6 Investigation of acute transfusion reactions, 65 Kathryn E. Webert & Nancy M. Heddle 7 Haemolytic transfusion reactions, 77 Edwin J. Massey, Robertson D. Davenport & Richard M. Kaufman 8 Febrile and allergic transfusion reactions, 89 Mark K. Fung & Nancy M. Heddle 9 Acute lung injury after transfusion, 97 Steven H. Kleinman & Ram Kakaiya 10 Purported adverse effects of transfusion-related immunomodulation and of the transfusion of old blood , 106 Eleftherios C. Vamvakas 11 Transfusion-associated graft-versus-host disease and microchimerism, 116 Beth H. Shaz, Richard O. Francis & Christopher D. Hillyer 12 Posttransfusion purpura, 127 Michael F. Murphy 13 Transfusion-transmitted infections, 132 Roger Y. Dodd & Susan L. Stramer 14 Bacterial contamination, 144 Sandra Ram'yrez-Arcos & Mindy Goldman 15 Variant Creutzfeldt Jakob disease, 152 Marc L. Turner 16 Emerging infections and transfusion safety, 161 Roger Y. Dodd Part Three: Practice in Blood Centres and Hospitals 17 Regulatory aspects of blood transfusion, 171 William G. Murphy, Louis M. Katz & Peter Flanagan 18 The role of haemovigilance in transfusion safety, 181 James P. AuBuchon & Katharine A. Downes 19 Donors and blood collection, 190 Ellen McSweeney & William G. Murphy 20 Blood donation testing and the safety of the blood supply, 201 Richard Tedder, Simon J. Stanworth & Mindy Goldman 21 Production and storage of blood components, 209 Rebecca Cardigan & Stephen Thomas 22 Medicolegal aspects of transfusion practice, 224 Patricia E. Hewitt 23 Blood transfusion in hospitals, 230 Erica M. Wood, Mark H. Yazer & Michael F. Murphy 24 Blood transfusion in a global context, 250 David J. Roberts, Alan D. Kitchen, Stephen Field, Imelda Bates & Jean Pierre Allain Part Four: Clinical Transfusion Practice 25 Inherited and acquired coagulation disorders, 263 Vickie McDonald & Samuel J. Machin 26 Massive blood loss, 276 Beverley J. Hunt & John R. Hess 27 Good blood management in acute haemorrhage and critical care, 284 Gavin J. Murphy, Nicola Curry, Nishith Patel & Timothy S. Walsh 28 Haematological disease, 300 Lise J. Estcourt, Simon J. Stanworth & Michael F. Murphy 29 Blood transfusion in the management of patients with haemoglobinopathies, 314 David C. Rees 30 Heparin-induced thrombocytopenia, 322 Andreas Greinacher & Theodore E. Warkentin 31 Immunodeficiency and immunoglobulin therapy, 335 Siraj A. Misbah 32 Fetal, neonatal and childhood transfusions, 347 Irene Roberts, Naomi Luban & Helen V. New 33 Recombinant proteins in diagnosis and therapy, 368 Marion Scott Part Five: Alternatives to Transfusion 34 Principles of patient blood management, 379 Aryeh Shander & Lawrence Tim Goodnough 35 Autologous transfusion, 390 Dafydd Thomas, Biddy Ridler & John Thompson 36 Blood substitutes, 399 David J. Roberts & Chris V. Prowse 37 Pharmacological agents and recombinant activated factor VIIa, 410 Beverley J. Hunt & Simon J. Stanworth Part Six: Cellular and Tissue Therapy and Organ Transplantation 38 Regulation and accreditation in cellular therapy, 421 Derwood H. Pamphilon & Zbigniew M. Szczepiorkowski 39 Stem cell collection and therapeutic apheresis, 433 Khaled El-Ghariani & Zbigniew M. Szczepiorkowski 40 Haemopoietic stem cell processing and storage, 443 Ronan Foley & Pamela O Hoski 41 Haemopoietic stem cell transplantation, 455 I. Grant McQuaker & Ian M. Franklin 42 Cord blood transplantation, 464 Rachael Hough 43 Recent advances in clinical cellular immunotherapy, 473 Mark W. Lowdell & Emma Morris 44 Tissue banking, 480 Akila Chandrasekar, Paul Rooney & John Kearney Part Seven: Development of the Evidence Base for Transfusion 45 Observational and interventional trials in transfusion medicine, 491 Alan Tinmouth, Dean Fergusson & Paul C. H'ebert 46 Getting the most out of the evidence for transfusion medicine, 505 Simon J. Stanworth, Susan J. Brunskill, Carolyn Doree, Sally Hopewell & Donald M. Arnold 47 Variation in transfusion practice and how to influence clinicians use of blood in hospitals, 516 Simon J. Stanworth, J.J. Francis, Michael F. Murphy & Alan T. Tinmouth 48 Scanning the future of transfusion medicine, 524 Dana V. Devine, Walter H. Dzik & Zbigniew M. Szczepiorkowski Index, 537 Colour plate section can be found facing page 432

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