Preface; List of contributors; Part I. Background: 1. Introduction Joyce Harper; 2. Assisted reproductive technologies Joyce Harper, Alpesh Doshi and Paul Serhal; 3. Genetic basis of inherited disease Joep Geraedts and Joy Delhanty; 4. Genetic counselling Alison Lashwood; 5. Prenatal screening and diagnosis Anna David and Charles Rodeck; 6. Preimplantation embryo development Kay Elder; 7. Preimplantation genetics Joy Delhanty and Dagan Wells; Part II. Procedures Used in PGD: 8. Clinical aspects of preimplantation genetic diagnosis Christine de Die-Smulders, Maartje van Rij and Johannes Evers; 9. Polar body biopsy techniques Markus Montag, Katrin van der Ven and Hans van der Ven; 10. Cleavage stage embryo biopsy Anick De Vos; 11. Blastocyst biopsy Monica Parriego, Francesca Vidal and Anna Veiga; 12. Preimplantation genetic diagnosis for chromosome rearrangements Caroline Mackie Ogilvie and Paul N. Scriven; 13. Preimplantation genetic diagnosis for infertility Santiago Munne; 14. Preimplantation genetic diagnosis for sex-linked diseases and sex-selection for non-medical reasons Caroline Mackie Ogilvie and Paul N. Scriven; 15. Preimplantation genetic diagnosis for monogenic disorders: multiplex PCR and whole genome amplification for gene analysis at the single cell level Karen Sermon; 16. Quality control and quality assurance in preimplantation genetic diagnosis Alan Thornhill and Sjoerd Repping; Part III. Ethics and the Future: 17. Preimplantation genetic testing: normative reflections Guido de Wert; 18. Preimplantation genetic diagnosis: the future Leeanda Wilton.
Describes all aspects of preimplantation genetic diagnosis with chapters written by key international experts in the field.
Joyce Harper is a Reader at UCL Centre for PGD, Institute for Women's Health, University College London, UK.
'… large educational value … enjoyable to read and easy to understand, also if you are far from being an expert in the field.' Acta Obstetricia et Gynecologica
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