Principles and Applications of Asymmetric Synthesis
Asymmetric synthesis remains a challenge to practicing scientists as the need for enantiomerically pure or enriched compounds continues to increase. Over the last decade, a large amount of literature has been published in this field. Principles and Applications of Asymmetric Synthesis consolidates and evaluates the most useful methodologies into a one-volume resource for the convenience of practicing scientists and students.
Authored by internationally renowned scientists in the field, this reliable reference covers more than 450 reactions and includes important stoichiometric as well as catalytic asymmetric reactions. The first chapter reviews the basic principles, common nomenclature, and analytical methods, and the remainder of the book is organized according to reaction type. The text examines such topics as:
Practicing chemists in the pharmaceutical, fine chemical, and agricultural professions as well as graduate students will find that Principles and Applications of Asymmetric Synthesis affords comprehensive and current coverage.
Preface. Abbreviations. Introduction. alpha-Alkylation and Catalytic Alkylation of Carbonyl Compounds. Aldol and Related Reactions. Asymmetric Oxidations. Asymmetric Diels-Alder and Other Cyclization Reactions. Asymmetric Catalytic Hydrogenation and Other Reduction Reactions. Applications of Asymmetric Reactions in the Synthesis of Natural Products. Enzymatic Reactions and Miscellaneous Asymmetic Syntheses. Index.
GUO-QIANG LIN, YUE-MING LI, and ALBERT S. C. CHAN are all professors in the Department of Chemical Technology at The Hong Kong Polytechnic University, Hong Kong, China.
"Lin and colleagues...consolidate and evaluate the most useful methodologies for producing enantiomerically pure or enriched compounds." (SciTech Book News, Vol. 25, No. 3, September 2001) "...a concise and fairly comprehensive overview..." (Angewandte Chemie, 15 October 2001) "...a very good review of basic asymmetric methodology that can be recommended to students of organic chemistry..." (Journal of Medicinal Chemistry, Vol. 44, No. 26 2001) "a well balanced survey of stereocontrolled methodologies and synthetic applications from which the reader can achieve valuable information." (ChemWeb, 14 January 2002) "There are many books on asymmetric synthesis, but this work...is one of the most useful and comprehensive" (Organic Process Research & Development)