1. History of Transgender Care of Youth 2. Models of Care and Current Guidelines for Care of Transgender Individuals

3. Puberty (a review of normal pubertal physiology and development)

4. GnRH agonists (mechanism, past studies, use in precocious puberty, drug options, surgical placement)

5. GnRHa for gender non-conformng youth (Rationale for, Studies of efficacy, Initiation and monitoring of GnRHa)

6. Psychosocial Side Effects of GnRHa

7. Medical Side Effects of GnRHa

8. Surgical Side Effects of GnRHa

9. Fertility and GnRHa treatment

10. Treatment with GnRH Agonists and Gender Affirming Hormones

11. Ethical considerations of GnRHa treatment and consent process

12. Emerging Developments

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