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Reversibility of Chronic Disease and Hypersensitivity, Volume 3
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Table of Contents

INTEGRATION OF THE MUSCULOSKELETAL AND NEUROLOGICAL SYSTEMS

Introduction

Entry of Environmental Pollutants: External and Internal Mechanisms of the Total Body Pollutant Load
External Pollutants
Internal Excitotoxins

Environmental Control for Reducing Total Body Load
ECU Construction and Maintenance
Use of the ECU
Summary

VASCULAR FUNCTION AND DYSFUNCTION

Introduction to the Cardiovascular System in Chemical Sensitivity

Physiology and Pollutant Damage to Vascular Perfusion: Changes in the Sympathetic Nervous System Function
Physiology of Vascular Perfusion
Autonomic Nervous System
Connective Tissue
Endothelins
Vascular Injury due to Pollutants
Neovascularization
Regional Perfusion Injury

Blood Volume

Effects of Pollutants on the Clotting System

Oxygen Extraction

Effects of Pollutants on Myocardial Cells


Types of Mechanisms in Vascular Damage
Nonimmune Mechanisms
Immune Mechanisms

Effects of Endocrine on the Vascular System

Pollutant Entry in Dyshomeostasis: Clinical Syndromes
Vasculitis
Small Vessel Vasculitis
Large Vessel Vasculitis
Hypersensitive Vasculitis
Eosinophilic Vasculitis
Recurrent Phlebitis
Cardiac Arrhythmias and Dysfunction
Sudden Cardiac Death
Hereditary Angioedema
Urticaria
Anaphylaxis
Cardiac Metabolic Syndrome
Cardiomyopathy
Myocarditis

Atherosclerosis
Environmental Aspects of Atherosclerosis
Cardiac Events and Hospital Admission
Changes in Heart Rate and Cardiac Function
Influence of Particulates
Pathophysiology Leading to Inflammation
Inflammation Mechanism
Myocardial Necrosis and Toxic Infarction
Cardioprotection
Apoptosis
Toxic Infarction
Triggering Agents of CAD

Heart Failure
Introduction
Heart Failure Pathology and Cell Communication
Heart Failure Pathophysiology
Energy-Starvation Hypothesis

Heart Failure Treatment
Classic Medical Treatment
Neural Humeral Activation
Emerging Therapeutic Options: Nutrients
Summary

Index

About the Author

William J. Rea is a thoracic, cardiovascular, and general surgeon with an added interest in the environmental aspects of health and disease. He received his MD from The Ohio State University and was chief of thoracic surgery at the Veteran's Hospital in Dallas. He has lectured on cardiovascular and thoracic surgery at the University of Texas S.W. Medical School and on environmental sciences at the University of Texas. Dr. Rea served on the board of the American Academy of Environmental Medicine and is currently a board member of the American Board of Environmental Medicine. Dr. Rea is a fellow of the American Academy of Environmental Medicine, the American College of Surgeons, and the Royal Society of Medicine. He was part of the team who resuscitated Governor John Connally when President Kennedy was shot. Kalpana D. Patel is a pediatrician with an added interest in the environmental aspects of health and disease. She serves as an assistant professor of pediatrics at the State University of New York at Buffalo. Dr. Patel was awarded the Jonathan Forman Gold Medal Award for outstanding research in environmental medicine and the Herbert J. Rinkel Award for outstanding teaching by the American Academy of Environmental Medicine. Dr. Patel has served as president of the American Board of Environmental Medicine and is currently a member of its executive committee. She has also served on the board of the American Academy of Environmental Medicine and is a diplomate of both the American Board of Pediatrics and the American Board of Environmental Medicine. Dr. Patel is a fellow of the American Academy of Environmental Medicine.

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