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Sequence-Specific DNA Binding Agents

New or Used: 47 copies from $148.45
New or Used: 47 copies from $148.45

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Chapter 1: DNA recognition by triple helix formation; Chapter 2: Interfacial inhibitors of human topoisomerase I; Chapter 3: Diversity of topoisomerase I inhibitors for cancer chemotherapy; Chapter 4: Slow DNA binding; Chapter 5: DNA Gene Targeting using Peptide Nucleic Acid (PNA); Chapter 6: Actinomycin D - Sixty years of progress in characterising a sequence-selective DNA binding agent; Chapter 7: Thermal denaturation of drug-DNA complexes - Tools and tricks; Chapter 8: Computer simulations of drug-DNA interactions - a personal journey; Chapter 9: The discovery of G-quadruplex telomere targeting drugs; Chapter 10: The Mechanism of Action of Telomestatin, a G-Quadruplex-Interactive Compound; Chapter 11: Riboswitches and Ribozymes


An excellent overview of the work being done in the exciting areas of discovering agents that exhibit selectivity and sequence specificity for DNA.Michael J Waring, who has been a pioneer in and made seminal contributions to this particular field.A comprehensive reference on this rapidly expanding a must excellent text book for a graduate course on this subject and a useful guide at the post-graduate level for biochemists as well as biophysicists. * ChemBioChem, 2007, 8, 459-460 (Fu-Mling Chen) *

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