The range of topics represent the diversity of critical problems between structural biology, biochemistry and biophysics, in which lies the fertile ground of drug development, biotechnology and new materials. The individual articles represent the state of the art in each area and provide a guide to the original literature in this rapidly developing field.
Preface.- Structural Genomics by NMR Spectroscopy; A. Gutmanas et al.- Investigation of Proteins in Living Bacteria with in-Cell NMR Experiments; V. Doetsch.- Protein-Membrane Interactions: Lessons from In Silico Studies; R.G. Efremov et al.- Anything Goes - Protein Structural Polymorphism; A.M. Gronenborn.- Tandem Interactions in the trp Repressor System may Regulate Binding to Operator DNA; O. Jardetzky, M.D. Finucane.- Basic Principles of RNA NMR Spectroscopy; P.J. Lukavsky.- Probabilistic Structure Calculation; W.Rieping et al.- Molecular Insights into PKR Activation by Viral Double-Stranded RNA; S.A. McKenna et al.- Structural Dynamic Approach as Rational Input for Drug Design; R. Sertchook et al.- Max Perutz: Chemist, Molecular Biologist, Human Rights Activist; J.M. Thomas.- Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance and Antibiotics Inactivation; A. Yonath.- Author Index.-