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Viruses, Pandemics, and Immunity


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Table of Contents

Chapter 1: Conquering Smallpox
Chapter 2: The Discovery of Microbes and the Dawn of Vaccines
Chapter 3: Viruses and the Emergence of Pandemics
Chapter 4: Immunity
Chapter 5: Spread and Mitigation of Pandemics
Chapter 6: Antiviral Therapies
Chapter 7: Vaccines
Epilogue: Toward a more pandemic resilient future

About the Author

Arup K. Chakraborty is Robert T. Haslam Professor of Chemical Engineering and Professor of Physics and Chemistry at MIT, where he also served as the Founding Director of the Institute for Medical Engineering and Science. He is a founding member of the Ragon Institute. Andrey S. Shaw, an immunologist, is Staff Scientist in Immunology and Oncology at Genentech and holds adjunct professorships at Washington University in St. Louis and at the University of California, San Francisco. Illustrator Philip J. S. Stork is a Professor at the Vollum Institute at Oregon Health and Science University.


"This remarkable book will take the reader on a fascinating journey-how scientists have developed a deep understanding of our immune system, how this system fights viruses, and how vaccines and antiviral therapies work. This human story addresses the many questions that people worldwide are grappling with during the current global pandemic."
-Arun Majumdar, Stanford University and Founding Director of ARPA-E

"Chakraborty and Shaw's book will satisfy the public thirst for an authoritative account of how destructive pandemics survive despite enormous growth in scientific understanding. Their sobering view of the challenges that remain-to understand antibody action and develop effective vaccines-deserves close attention."
-John Deutch, Former Provost Institute Professor Emeritus, MIT

"The authors provide a readily accessible introduction to viruses, a class of tiny human pathogens with surprising potential to cause transmissible, sometimes fatal, disease. They speak from a deep understanding of the viruses and the body's response to viral infections. A great book for people who want to understand why viruses are such a challenge to human life."
-David Baltimore, Professor, California Institute of Technology, 1975 Nobel Prize in Medicine for work in virology

"This is a wonderful book that beautifully explains, in a very easy-to-read and understandable way, the history of pandemics and how the diseases that cause them may be conquered."
-Robert Langer, Institute Professor, MIT, and recipient of the US National Medal of Science and the US National Medal of Technology and Innovation

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