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Cutting-edge reviews concerning the molecular and cellular biology of vitamins and hormones

Table of Contents

Table of ContentsEnzymatic formation of anandamideY. Okamoto, K. Tsuboi and N. UedaOrganized trafficking of anandamide and related lipidsM.L. Yates and E.L. BarkerBiosynthesis of oleamideG.P. Mueller and W.J. DriscollAnandamide receptor signal transductionC.E. Goodfellow and M. GlassIs GPR55 an anandamide receptor?A.J. Brown and C.R. HileyThe endocannabinoid system during development; emphasis on perinatal events and delayed effectsE. Fride, N. Gobshtis, H. Dahan, A. Weller, A. Giuffrida and S. Ben-ShabatCannabinoid receptor CB1 antagonists: state of the art and challengesM. Bifulco, A. Santoro, C. Laezza and A.M. MalfitanoNovel endogenous N-acyl glycines: Identification and characterizationH.B. Bradshaw, N. Rimmerman, S.S.-J. Hu, S. Burstein and the late J.M. WalkerThe endocannabinoid anandamide: from immunomodulation to neuroprotection, implications for multiple sclerosisF.G. Correa, L. Mestre, F. Docagne, J. Borrell and C. GuazaModulation of the endocannabinoid-degrading enzyme fatty acid amide hydrolase by follicle-stimulating hormoneP. Grimaldi, G. Rossi, G. Catanzaro and M. MaccarroneGlucocorticoid-regulated crosstalk between arachidonic acid and endocannabinoids biochemical pathways coordinates cognitive-, neuroimmune- and energy homeostasis-related adaptations to stressR. Malcher-Lopes and M. BuzziModulation of the Cys-loop ligand-gated ion channels by fatty acid and cannabinoidsL. Zhang and W. XiongEndogenous cannabinoids and neutrophil chemotaxisD. McHugh and R.A. RossCB1 activity in male reproduction: mammalian and non-mammalian animal modelsR. Pierantoni, G. Cobellis, R. Meccariello, G. Cacciola, R. Chianese, T. Chioccarelli and S. FasanoAnandamide and the vanilloid receptor (TRPV1)A. Toth, P.M. Blumberg and J. BoczanEndocannabinoid system and fear conditioningL.B.M. Resstel, F.A. Moreira and F.S. GuimaraesRegulation of gene transcription and keratinocyte differentiation by anandamideN. Pasquariello, S. Oddi, M. Malaponti and M. MaccarroneChanges in the endocannabinoid system may give insight into new and effective treatments for cancerG. Alpini and S. DeMorrowUse of cannabinoids as a novel therapeutic modality against autoimmune hepatitisR. Panday, V. Hegde, N. Singh, L. Hofseth, U. Singh, S. Ray, M. Nagarkatti and P. Nagarkatti

About the Author

Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.