Table of Contents

Preface. Foreword. Dose (Dosage and Other Factors Influencing Toxicity. Chemistry of Pesticides. Pest Control Agents from Natural Products. Public Health Pesticides. Lawn and Turf: Management and Environmental Issues of Turfgrass Pesticides. Insecticides and Their Use in Urban Structural Pest Control. Verterbrate Pest Control Chemicals and Their Use in Urban and Rural Envrionments. Pesticide Use in Veterinary Medicine. Pesticide Use Practices in Integrated Pest Management. Toxicity Testing. Regulatory Evaluation of the Skin Effects of Pesticides. Neurophysiological Effect of Insecticides. Ecotoxicological Risk Assessment of Pesticides in the Environment. Developmental and Reproductive Toxicology of Pesticides. Worker Exposure: Methods and Techniques. Residential Exposure Assessment: An Overview. Modeling Dietary Exposure with Special Secitons on Meodeling Aggregate and Cumulative Exposure. Greenhouse and Mushroom House Exposure Coping with Aggregate Pesticide Exposure Assessment: An Integration Approach. Occupational Exposure Data Bases/Models for Pesticides. Factors that Affect Pesticide Metabolism and Toxicity. Pesticide Disposition Dermal Absorption. Metabolism of Pesticides. Absorption, Distribution, and Pharmacokinetics. Pesticide Excretion. Diagnosis and Treatment of Poisoning Due to Pesticides. Surveillance of Pesticide-Related Illness and Injury in Humans. Environmental Transport and Fate. Hydrophobicity as a Key Physicochemical Parameter of Environmental Toxociology of Pesticides. Modern Approaches to Analysis of Pesticide Residues in Foods and the Environment. Risk Assessment and Risk Management: The Regulatory Process. Risk Assessment for Acute Exposure to Pesticides. Risk Assessment for Chronic Exposure to Pesticides: The Triazine Herbicide Cyanazine. Pesticides as Endocrine-Disrupting Chemicals. Genetic Toxicity of Pesticides. Immunotoxicity of Pesticides. Sensitive Population Groups. Pesticide Residues in Food and Cancer Risk: A Critical Analysis. Perceptions of Pesticides as Risks to Human Health. Mammalian Toxicity of Microbial Pest Control Agents. The Influence of Age on Pesticide Toxicity. Emerging Issues: Children's Exposure to Pesticides in Residential Settings . Pesticide Percutaneous Absorption and Decontamination. Chemistry of Organophosphorus Insectides. The Metabolism of Organophosphorus Insecticides. Organophosphate Pharmacokinetics. Neuropathy Target Esterase. Cholinesterases. Organophosphorus-Induced Delayed Neuropathy. Understanding the Toxic Actions of Organophosphates. Clinical Toxicology of Anticholinesterase Agents in Humans. Carbomate Insecticides. Aldicarb: Current Science-Based Approaches in Risk Assessment. Imidacloprid A Neonicotinoid Insecticide Interactions with the gamma-Aminobytyric Acid A-Receptor Polychlorocycloalkanes and Recent Congeners. The Avermectins: Insecticidal and Antiparasitic Agents. Inhibitors and Uncouplers of Mitochondrial Oxidative Phosphorylation. Pyrethroid Chemistry and Metabolism. Pyrethroid Insecticides: Mechanisms of Toxicity, Systemic Poisoning Syndromes, Parathesia, and Therapy. DDT and its Analogs. Inorganic and Organometal Pesticides. Boric Acid and Inorganic Borate Pesticides. Deet. The Safety Assessment of Piperonyl Butoxide. Pentachlorophenol. Symmetrical and Asymmetrical Triazine Herbicides. Phenylurea Herbicides. Protoporphyrinogen Oxidase Inhibitors. Chloracetanilides. Paraquat. Diquat. Phenoxy Herbicides. Dicamba. Imidazolinones. Toxicology of Triazolopyrimidine Herbicides. Inhibitors of Aromatic Acid Biosynthesis. Fungicides. Cyprodinil. Captan and Folpet. Chlorothalonil. Dialkyldithiocarbamates. A Toxicological Assessment of Sulfur as a Pesticide. Rodenticides. Methyl Bromide. Dichloropropene. Phosphine. Metam-Sodium. Sulfuryl Fluoride.

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Key Features
* Establishes a context for evaluation of pesticide use in agriculture, residential pest control and public health described
* Important discussion of strategies for pesticide risk assessment
* All major classes of pesticide considered
* Different routes of exposure critically evaluated
* Current regulatory issues defined
* Emerging issues concern topics of special relevance in the future
* Agents reviewed by experts from academia, government research, and the private sector

Reviews

"These are the two volumes you need to have ready access to if you have any association with pesticide actions, use, or environmental/biological effectiveness. ...it will remain a standard for many years." -VET HUMAN TOXICOLOGY (August 2002) "I have found that the Handbook of Pesticide Toxicology has been a great asset...it is a revision that every toxicologist should include in recommendations to their institutional library. As a comprehensive work, it stands above others in the field." -John Edwards for THE BRITISH TOXICOLOGY SOCIETY NEWSLETTER (Spring 2002) "This is highly recommended, not only for professional toxicologists working with pesticides, but also as a notable source of information on mechanistic toxicology and risk assessment." -Philip Harvey for THE BRITISH TOXICOLOGY SOCIETY NEWSLETTER (Spring 2002)