Table of Contents

Section I. Foundations and Principles of Geriatric Neurology 1. Geriatric pharmacotherapy: Appraising new drugs for neurological disorders in older patients 2. Animal models of cognitive aging and circuit-specific vulnerability 3. Psychopharmacology and pharmacokinetics 4. Models of care 5. Neurologic examination in the elderly 6. Cognitive and neuropsychological evaluation of the elderly 7. Chronic neurological disorders and related comorbidities: Role of age-associated physiological changes 8. Autonomic dysfunction: diagnosis and management 9. Epidemiology of aging and associated neurological disorders: Prevalence and incidence of Alzheimer disease and other dementias 10. Neuropsychology of aging 11. Cognitive reserve 12. Neuroimaging in aging and neurological diseases

Section II. Neurological Disorders of Late-Life 13. Alzheimer disease 14. Parkinson disease – diagnosis and appreciation of comorbidities 15. Frontotemporal dementia 16. Recognizing and treating atypical Parkinson disorders 17. Down syndrome 18. The long-term consequences of repetitive head impacts: Chronic traumatic encephalopathy 19. Delirium in the critically ill patient 20. Vascular cognitive impairment: a preventable component of dementia 21. Stroke in the elderly 22. Gait and dementia 23. Assessment and treatment of major depression in older adults 24. Neuropsychiatric symptoms in dementia 25. Epilepsy and aging 26. Sleep physiology and disorders in aging and dementia

Section III. General Topics in Geriatric Neurology 27. Urological function and dysfunction in aging: Diagnosis and treatment 28. Geriatric rehabilitation 29. Palliative medicine and end-of-life care 30. Headache in the elderly 31. Driving in the elderly in health and disease 32. The evolution of geriatric neurology

About the Author

Steven T. DeKosky is Professor of Neurology and Neuroscience and Deputy Director of the McKnight Brain Institute at the University of Florida, Gainesville, FL, USA, where he holds the Aerts-Cosper Professorship in Alzheimer Research. Before moving to the University of Florida, he was vice president and dean of the University of Virginia School of Medicine, and the James Carroll Flippin Professor of Medical Sciences. He was Professor and Chair of the Department of Neurology and Director of the Pitt/UPMC Alzheimer’s Disease Research Center, and served as a member of the American Board of Psychiatry and Neurology. Sanjay Asthana is Associate Dean for Gerontology and Professor and Head of the Division of Geriatrics & Gerontology at the UW-Madison School of Medicine and Public Health. He holds the Duncan G. and Lottie H. Ballantine endowed chair in geriatrics and serves as Director of both the Wisconsin Alzheimer’s Disease Research Center and the Geriatric Research, Education and Clinical Center at the William S. Middleton Memorial Veterans Hospital in Madison, Wisconsin. Prior to coming to UW, he served as a faculty at the University of Washington School of Medicine in Seattle, Washington.