Overview of Resistance to Systemic Therapy in Patients with Breast Cancer.- Roles of Multidrug Resistance Genes in Breast Cancer Chemoresistance.- Therapy-Induced Apoptosis in Primary Tumors.- Cell Cycle Deregulation in Breast Cancer: Insurmountable Chemoresistance or Achilles’ Heel?.- p53, BRCA1 and Breast Cancer Chemoresistance.- Integrin-Mediated Adhesion: Tipping the Balance between Chemosensitivity and Chemoresistance.- Insulin-Like Growth Factors and Breast Cancer Therapy.- EGF Receptor in Breast Cancer Chemoresistance.- Molecular Mechanisms of ErbB2-Mediated Breast Cancer Chemoresistance.- Estrogen Receptors in Resistance to Hormone Therapy.- Novel Approaches for Chemosensitization of Breast Cancer Cells: The E1A Story.

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