Table of Contents

1. INTRODUCTION. 1.1 Historical Prelude, 1.2 Basic Cell Biology, 1.3 The Extracellular Matrix, 1.4 Soft Tissue Behavior, 1.5 Needs and General Approach, 1.6 Exercises, 1.7 References. 2. MATHEMATICAL PRELIMINARIES 2.1 A Direct Tensor Notation, 2.2 Cartesian Components, 2.3 Further Results in Tensor Calculus, 2.4 Orthogonal Curvilinear Components, 2.5 Matrix Methods, 2.6 Exercises, 2.7 References, 3. CONTINUUM MECHANICS 3.1 Kinematics, 3.2 Forces, Tractions and Stresses, 3.3 Balance Relations, 3.4 Constitutive Formulations, 3.5 Boundary and Initial Conditions, 3.6 Exercises, 3.7 References, 4. FINITE ELASTICITY 4.1 Introduction, 4.2 Incompressible Isotropic Elasticity, 4.3 Solutions in 3-D Incompressible Elasticity, 4.4 Compressible Isotropic Elasticity, 4.5 Membrane Hyperelasticity, 4.6 Exercises, 4.7 References 5. EXPERIMENTAL METHODS 5.1 General Philosophy, 5.2 Measurement of Strain, 5.3 Measurement of Applied Loads, 5.4 Testing Conditions, 5.5 Parameter Estimation and Statistics, 5.6 Exercises, 5.7 References 6. Finite Element Methods 6.1 Fundamental Equations, 6.2 Interpolation, Integration, and Solvers, 6.3 An Illustrative Formulation, 6.4 Inflation of a Membrane, 6.5 Inverse Finite Elements, 6.6 Exercises, 6.7 References PART II - VASCULAR MECHANICS 7. THE NORMAL ARTERIAL WALL 7.1 Structure and Function, 7.2 General Characteristics, 7.3 Constitutive Framework, 7.4 Experimental Methods, 7.5 Specific Constitutive Relations, 7.6 Stress Analyses, 7.7 Exercises, 7.8 References 8. VASCULAR DISORDERS 8.1 Hypertension, 8.2 Intracranial Aneurysms, 8.3 Atherosclerosis, 8.4 Aortic Aneurysms, 8.5 Additional Topics, 8.6 Exercises, 8.7 References 9. VASCULAR ADAPTATION 9.1 Mechanical Preliminaries, 9.2 Cellular Responses to Applied Loads, 9.3 Arterial Response to Hypertension, 9.4 Arterial Response to Altered Flow, 9.5 Vessel Response to Injury, 9.6 Veins as Arterial Grafts, 9.7 Aging, 9.8 Exercises, 9.9 References PART III CARDIAC MECHANICS 10. THE NORMAL HEART 10.1 Structure and Function, 10.2 General Characteristics, 10.3 Constitutive Framework, 10.4 Constitutive Relations, 10.5 Stress Analyses, 10.6 Exercises, 10.7 References 11. EPILOGUE APPENDICES I. Nomenclature, Abbreviations, and Conversions II. Results for Curvilinear Coordinates III. Material Frame Indifference 11. CARDIAC DISORDERS 11.1 Ischemia 11.2 Volume Overload 11.3 Hypertrophy 11.4 Cardiac Aneurysms 11.5 Additional Topics