A comprehensive reference on the science, diagnosis and treatment of peripheral nerve disorders
Section 1 Introduction 1. Prelude to the peripheral neuropathies Section 2 Structure and function 2. Microscopic anatomy: normal structures; 3. Gross anatomy and development of the peripheral nervous system; 4. Physiology and pathophysiology of myelinated nerve fibers; 5. Biology of Schwann cells; 6. Neurophysiological approach to disorders of peripheral nerve; 7. Testing autonomic functions; 8. Imaging of the peripheral nervous system; 9. The nerve biopsy: indications, technical aspects and contribution; 10. The cutaneous nerve biopsy: Technical aspects, indications, and contribution; 11. Antibody testing in peripheral nerve disorders; 12. DNA testing in hereditary neuropathies Section 3 Clinical aspects 13. Examination and clinical care of the patient with neuropathy; 14. How to explore a patient with chronic axonal neuropathy; 15. Evaluation of a patient with suspected chronic demyelinating polyneuropathy; 16. Sensory-motor assessment in clinical research trials; 17. Management of painful neuropathies Section 4 Plexus and compression lesions 18. Diagnosis of brachial and lumbosacral plexus lesions; 19. Compression and entrapment neuropathies; 20. Facial nerve palsy and hemifacial spasm Section 5 Inflammatory root and nerve lesions 21. The Guillain-Barré syndrome; 22. Chronic inflammatory demyelinating polyneuropathy; 23. Treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP); 24. Multifocal motor neuropathy 25. Neuropathy and monoclonal gammopathy Section 6 Neuropathy in connective tissue disorders 26. Vasculitic neuropathy; 27. Sarcoidosis of the peripheral nervous system Section 7 Neuropathy in infectious disorders 28. Leprous neuropathy; 29. HIV peripheral neuropathy; 30. Human t-cell leukemia virus (HTLV) associated neuropathy; 31. Herpes virus infection of the peripheral nervous system; 32. Lyme neuroborreliosis Section 8 Neuropathy and metabolic disorders 33. Diabetic neuropathy; 34. Biology of diabetic neuropathy; 35. Uremic neuropathy; 36. Porphyric neuropathy; 37. Fabry’s disease; 38. Transthyretin familial amyloid polyneuropathy; 39. Hereditary gelsolin amyloidosis Section 9 Neuropathy and malignancy 40. Malignant cell infiltration in the peripheral nervous system; 41. Paraneoplastic neuropathy Section 10 Cryptogenic, Traumatic and Iatrogenic neuropathies 42. Drug induced neuropathies; 43. Late radiation injury to peripheral nerves; 44. Neuromuscular complications of critical illness; 45. The surgery of peripheral nerves (including tumours); 46. Neuropathy in the elderly Section 11. Familial neuropathies 47. Dominant Charcot-Marie-Tooth syndrome and cognate disorders; 48. Recessively transmitted predominantly motor neuropathies; 49. Early onset childhood monogenic neuropathies; 50. Hereditary sensory and autonomic neuropathies; 51. Peripheral nerve involvement in hereditary cerebellar and multisystem degenerative disorders; 52. Giant axonal neuropathy; 53. Neurofibromatosis 1(NF1), diagnosis and management; 54. Neurofibromatosis type 2 (NF2) diagnosis and management
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