This volume represents the most relevant and up-to-date information pertaining to the fields of traumatic brain injury (TBI) and spinal cord injury (SCI).
I. INTRODUCTION:
1. The impact of neurotrauma on society: an international
perspective.
II. BIOMECHANICS OF INJURY:
2. CNS injury biomechanics and experimental models
3. Linking impact to cellular and molecular sequelae of CNS injury:
modelling in vivo complexity with in vitro simplicity
III. PATHOLOGICAL MECHANISMS OF INJURY
4. Cellular and subcellular change evoked by diffuse traumatic
brain injury – a complex web of change extending far beyond focal
damage.
5. Astrologia: important mediators of traumatic brain injury.
6. Rescuing neurons and glia: is inhibition of apoptosis
useful?
7. Substance P in traumatic brain injury.
8. Current concepts of cerebral oxygen transport and energy
metabolism after severe traumatic brain injury.
9. Progressive damage after brain and spinal cord injury:
pathomechanisms and treatment strategies.
10. Injury-induced alterations in CNS electrophysiology.
11. Traumatic injury of the spinal cord and nitric oxide.
12. Aquaporins: role in cerebral edema and brain water balance.
13. Sodium channel expression and the molecular pathophysiology of
pain after SCI.
IV. NOVEL ASPECTS OF CLINICAL RESEARCH IN CNS INJURY
14. Monitoring cerebral oxygenation in traumatic brain injury.
15. Update on the treatment of spinal cord injury.
16. Cerebral contusion: a role for lesion progression.
17. Ethical implications of time frames in a randomized controlled
trial in acute severe traumatic brain injury.
V. EMERGING TOPICS IN CNS TRAUMA
18. Experimental models of repetitive brain injuries.
19. Minor traumatic brain injury in sports: a review in order to
prevent neurological sequelae.
20. Traumatic brain injury in infants: the phenomenon of subdural
hemorrhage with hemispheric hypodensity (“Big Black Brain).
21. Traumatic brain injury and Alzheimer’s disease: a review.
22. The neurotrophic protein S100B: Value as a marker of brain
damage and possible therapeutic implications.
23. Cerebellar injury: clinical relevance and potential in
traumatic brain injury research.
24. Sex differences in brain damage and recovery of function:
experimental and clinical findings.
25. Heat acclimation: a unique model of physiologically mediated
global preconditioning against traumatic brain injury.
VI. THE FUTURE OF NEUROTRAUMA: DEVELOPING NOVEL TREATMENT
STRATEGIES
26. In vivo tracking of stem cells in brain and spinal cord
injury.
27. Intrathecal drug delivery strategy is safe and efficacious for
localized delivery to the spinal cord.
28. Decompression craniectomy after traumatic brain injury – recent
experimental results.
29. Novel neuroproteomic approaches to studying traumatic brain
injury.
30. Remyelination of the injured spinal cord
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